20755-09-3

Upstream product

• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 487-25-2 2',4-dihydroxydihydrochalcone 
• 487-26-3 Flavanone 
• 64-19-7 acetic acid 
• 487-25-2 cis-4-hydroxyflavan 
• 525-82-6 FLAVONE 
• 108-24-7 acetic anhydride 

Downstream Products

• 41886-75-3 (2R,4R)-(-)-cis-4-hydroxyflavan 
• 55568-97-3 (2R,3R)-3-hydroxyflavanone 
• 476310-80-2 (2R,4R)-flavan-4-ol acetate 
• 142696-01-3 (2S,4S)-(+)-cis-4-acetoxyflavan 
• 487-26-3 (2S)-flavanone 
• 487-26-3 (R)-flavanone 
• 96790-73-7 (2S,3S)-3-hydroxyflavanone 

Relevant academic research and scientific papers

Enantioselective acylation of (±)-cis-flavan-4-ols catalyzed by lipase from Candida cylindracea (CCL) and the synthesis of enantiopure flavan-4-ones

Lipase Candida cylindracea (CCL) catalyzed acylation of (±)-cis-flavan-4-ols using vinyl acetate as the acyldonor in DME-toluene (1:2) gave (-)-(2R,4R)-4-acetoxyflavans 9a-m and (+)-(2S,4S)-flavan-4-ols 10a-m in high enantiomeric excess. (+)-(2S,4S)-Flava

Epimerisation of 4-Acetoxyflavans and Flavan-4-ols

5,7,3',4'-Tetramethoxyflavan-4β-ol reacts at 0 deg C with pyridine, ang a trace of acetic acid to give the 4β-acetoxy derivative but at 90 deg C the 4α-acetoxyflavan is formed.Either acetate when equilibrated with this acetylating agent yields a mixture o