4766-45-4

Usage

Chemical compound

4-(2-amino-2-phenylethyl)phenol

Molecular structure

Consists of a phenol group linked to a 2-amino-2-phenylethyl substituent

Uses

Production of pharmaceuticals, intermediate in organic synthesis

Application

Medicinal chemistry, particularly in drugs targeting neurological disorders and cancer

Research

Investigating pharmacological properties and potential therapeutic benefits

Regulation

Subject to regulatory controls and safety assessments

Significance

Plays a role in scientific and industrial applications in chemistry and pharmaceutical sciences.

Upstream product

• 67-56-1 methanol 
• 622-42-4 1-nitro-1-phenylmethane 
• 4397-53-9 p-benzyloxybenzaldehyde 

Downstream Products

• 4766-45-4 (+)-4-(2-amino-2-phenyl-ethyl)-phenol 
• 4766-45-4 (-)-4-(2-amino-2-phenyl-ethyl)-phenol 
• 63384-27-0 4-[2-(4-cyclohexyl-piperazin-1-yl)-2-phenyl-ethyl]-phenol 

Relevant academic research and scientific papers

Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties

There is provided a method of treatment of neurological disorders, such as epilepsy, stroke and cerebral ischaemia, which comprises the administration of a compound of Formula I: STR1 wherein, Ar1 and Ar2, which may be the same or different, independently represent phenyl or phenyl substituted by one or more of amino, nitro, halogen, hydroxy, C1 to 6 alkoxy, C1 to 6 alkyl or cyano; R1 represents hydrogen, C1 to 6 alkyl, C1 to 6 alkoxycarbonyl; R2 represents hydrogen or COCH2 NH2 ; R3 represents hydrogen or C1 to 6 alkyl; in addition, when R2 represents hydrogen either one or both of Ar1 and Ar2 may also represent 2-, 3- or 4-pyridinyl and R1 may also represent trihalomethyl; or a pharmaceutically acceptable salt thereof. Some of the compounds of formula I are novel, and these are also provided, together with pharmaceutical compositions containing the novel compounds.