476660-41-0

Basic information

• Product Name: 4-Chloro-2-methyl-5-nitrobenzoic acid 97+%
• Synonyms: 4-Chloro-2-methyl-5-nitrobenzoic acid 97+%;4-Chloro-5-nitro-o-toluic acid, 2-Carboxy-5-chloro-4-nitrotoluene;4-Chloro-2-methyl-5-nitrobenzoic acid
• CAS NO: 476660-41-0
• Molecular Formula: C₈H₆ClNO₄
• Molecular Weight: 216
• Mol File: 476660-41-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 394.4±42.0 °C(Predicted)
• Appearance: /
• Density: 1.517±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.04±0.12(Predicted)
• CAS DataBase Reference: 4-Chloro-2-methyl-5-nitrobenzoic acid 97+%(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-2-methyl-5-nitrobenzoic acid 97+%(476660-41-0)
• EPA Substance Registry System: 4-Chloro-2-methyl-5-nitrobenzoic acid 97+%(476660-41-0)

Safety Data

• Hazardous Substances Data: 476660-41-0(Hazardous Substances Data)

Usage

General Description

4-Chloro-2-methyl-5-nitrobenzoic acid 97+% is a chemical compound that is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is a white to yellow crystalline powder with a molecular formula of C8H6ClNO4. The compound is known for its high purity of 97% or greater, making it suitable for a wide range of research and industrial applications. It is important to handle this chemical with care, as it may be harmful if ingested or inhaled, and can cause irritation to the skin and eyes. Additionally, it should be stored in a cool, dry, and well-ventilated area away from incompatible materials.

Upstream product

• 7499-07-2 4-chloro-2-methylbenzoic acid 
• 178448-14-1 4-chloro-2-methyl-5-nitrobenzonitrile 
• 717912-91-9 1-(4-chloro-2-methyl-5-nitro-phenyl)-ethanone 
• 7732-18-5 water 
• 7487-88-9 magnesium sulfate 
• 50712-68-0 4-chloro-2-methylbenzonitrile 
• 120-66-1 N-(2-methylphenyl)acetamide 
• 95-69-2 4-chloro-2-methylbenzeneamine 

Downstream Products

• 40319-46-8 3,5-dinitro-4-chloro-o-toluic acid 
• 190367-56-7 methyl 4-chloro-2-methyl-5-nitrobenzoate 
• 190367-57-8 4-chloro-2-methyl-3-nitrobenzoic acid methyl ester 
• 863885-79-4 methyl 2-methyl-4-(methylamino)-5-nitrobenzoate 
• 18018-35-4 1-chloro-5-methyl-2-nitro-4-(trifluoromethyl)benzene 

Relevant articles and documents

Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis

The presence and growth of endometrial tissue outside the uterine cavity in endometriosis patients are primarily driven by hormone-dependent and inflammatory processes - the latter being frequently associated with severe, acute, and chronic pelvic pain. T

Viral polymerase inhibitors

An isomer, enantiomer, diastereoisomer, or tautomer of a compound, represented by formula I: wherein R1 is selected from: H, haloalkyl, (C1-6)alkyl, (C2-6)alkenyl, (C3-7)cycloalkyl, (C2-6)alkynyl, (C5-7)cycloalkenyl, 6 or 10-membered aryl, Het all optionally substituted; R2 is selected from (C1-6)alkyl, (C3-7)cycloalkyl, (C6-10)bicycloalkyl, 6- or 10-membered aryl, or Het all optionally substituted; B is N or CR5, wherein R5 is H, halogen, haloalkyl, (C1-6)alkyl, (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; X is N or CR5; D is N or CR5; each of Y1 and Y2 is independently O or S; Z is O, N, or NRz wherein Rz is H, (C1-6)alkyl, (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; R3 and R4 are each independently H, (C1-6)alkyl, first (C3-7)cycloalkyl or 6- or 10-membered aryl, Het (C1-6)alkyl-6- or 10-membered aryl, (C1-6)alkyl-Het; or each R3 and R4 are independently covalently bonded together to form second (C3-7)cycloalkyl, or heterocycle, all optionally substituted; or when Z is N, either R3 or R4 are independently covalently bonded thereto to form a nitrogen-containing heterocycle; R7 is H, (C1-6 alkyl), (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; or R7 is covalently bonded to either of R3 or R4 to form a heterocycle; A is (C1-6) alkyl-CONHR8 wherein R8 is-6- or 10-membered aryl, or Het; or A is a 6- or 10-membered aryl, or Het said aryl or Het being optionally substituted; or a salt or a derivative thereof; such compounds being potent inhibitors of HCV NS5B polymerase.