476660-41-0

Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-2-methyl-5-nitrobenzoic acid 97+% is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Chloro-2-methyl-5-nitrobenzoic acid 97+% serves as an essential building block for the production of various agrochemicals, including pesticides and herbicides. Its incorporation into these products helps improve their effectiveness in controlling pests and weeds, thereby enhancing crop yields.
Used in Dye Industry:
4-Chloro-2-methyl-5-nitrobenzoic acid 97+% is utilized as a crucial intermediate in the manufacturing of dyes. Its chemical properties contribute to the development of dyes with specific color characteristics and improved performance in various applications, such as textiles, plastics, and printing inks.
Used in Research Applications:
Due to its high purity and unique chemical structure, 4-Chloro-2-methyl-5-nitrobenzoic acid 97+% is widely used in research settings. It serves as a valuable compound for studying various chemical reactions, exploring new synthesis pathways, and developing innovative applications across different industries.

Upstream product

• 7499-07-2 4-chloro-2-methylbenzoic acid 
• 178448-14-1 4-chloro-2-methyl-5-nitrobenzonitrile 
• 717912-91-9 1-(4-chloro-2-methyl-5-nitro-phenyl)-ethanone 
• 7732-18-5 water 
• 7487-88-9 magnesium sulfate 
• 50712-68-0 4-chloro-2-methylbenzonitrile 
• 95-69-2 4-chloro-2-methylbenzeneamine 
• 120-66-1 N-(2-methylphenyl)acetamide 

Downstream Products

• 40319-46-8 3,5-dinitro-4-chloro-o-toluic acid 
• 190367-56-7 methyl 4-chloro-2-methyl-5-nitrobenzoate 
• 190367-57-8 4-chloro-2-methyl-3-nitrobenzoic acid methyl ester 
• 863885-79-4 methyl 2-methyl-4-(methylamino)-5-nitrobenzoate 
• 18018-35-4 1-chloro-5-methyl-2-nitro-4-(trifluoromethyl)benzene 

Relevant academic research and scientific papers

Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis

The presence and growth of endometrial tissue outside the uterine cavity in endometriosis patients are primarily driven by hormone-dependent and inflammatory processes - the latter being frequently associated with severe, acute, and chronic pelvic pain. T

BENZOIMIDAZOLE DERIVATIVES AS PAD4 INHIBITORS

Compounds of formula (I): wherein X, Y, R1 and R3-R11 are as herein defined, and salts thereof are PAD4 inhibitors and may be useful in the treatment of various disorders, for example rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosis, and psoriasis.

Viral polymerase inhibitors

An isomer, enantiomer, diastereoisomer, or tautomer of a compound, represented by formula I: wherein R1 is selected from: H, haloalkyl, (C1-6)alkyl, (C2-6)alkenyl, (C3-7)cycloalkyl, (C2-6)alkynyl, (C5-7)cycloalkenyl, 6 or 10-membered aryl, Het all optionally substituted; R2 is selected from (C1-6)alkyl, (C3-7)cycloalkyl, (C6-10)bicycloalkyl, 6- or 10-membered aryl, or Het all optionally substituted; B is N or CR5, wherein R5 is H, halogen, haloalkyl, (C1-6)alkyl, (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; X is N or CR5; D is N or CR5; each of Y1 and Y2 is independently O or S; Z is O, N, or NRz wherein Rz is H, (C1-6)alkyl, (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; R3 and R4 are each independently H, (C1-6)alkyl, first (C3-7)cycloalkyl or 6- or 10-membered aryl, Het (C1-6)alkyl-6- or 10-membered aryl, (C1-6)alkyl-Het; or each R3 and R4 are independently covalently bonded together to form second (C3-7)cycloalkyl, or heterocycle, all optionally substituted; or when Z is N, either R3 or R4 are independently covalently bonded thereto to form a nitrogen-containing heterocycle; R7 is H, (C1-6 alkyl), (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; or R7 is covalently bonded to either of R3 or R4 to form a heterocycle; A is (C1-6) alkyl-CONHR8 wherein R8 is-6- or 10-membered aryl, or Het; or A is a 6- or 10-membered aryl, or Het said aryl or Het being optionally substituted; or a salt or a derivative thereof; such compounds being potent inhibitors of HCV NS5B polymerase.