190367-56-7

Basic information

• Product Name: Methyl 4-chloro-2-Methyl-5-nitrobenzoate
• Synonyms: Methyl 4-chloro-2-Methyl-5-nitrobenzoate;4-Chloro-2-methyl-5-nitro-benzoic acid methyl ester
• CAS NO: 190367-56-7
• Molecular Formula: C₉H₈ClNO₄
• Molecular Weight: 229.61712
• Mol File: 190367-56-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 335.8±37.0 °C(Predicted)
• Appearance: /
• Density: 1.371±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 4-chloro-2-Methyl-5-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-chloro-2-Methyl-5-nitrobenzoate(190367-56-7)
• EPA Substance Registry System: Methyl 4-chloro-2-Methyl-5-nitrobenzoate(190367-56-7)

Safety Data

• Hazardous Substances Data: 190367-56-7(Hazardous Substances Data)

Usage

General Description

Methyl 4-chloro-2-methyl-5-nitrobenzoate is a chemical compound with the molecular formula C9H8ClNO4. It is a yellow crystalline solid often used in the production of pharmaceuticals and agrochemicals. Methyl 4-chloro-2-Methyl-5-nitrobenzoate is commonly synthesized through the esterification of 4-chloro-2-methyl-5-nitrobenzoic acid with methanol, and it is known for its high purity and stability. Methyl 4-chloro-2-methyl-5-nitrobenzoate has been found to exhibit antimicrobial and anti-inflammatory properties, making it a valuable ingredient in various medicinal and agricultural applications. Additionally, it is important to handle this chemical with care, as it may cause skin and eye irritation and can be harmful if ingested or inhaled.

Upstream product

• 67-56-1 methanol 
• 476660-41-0 4-chloro-2-methyl-5-nitrobenzoic acid 
• 7499-07-2 4-chloro-2-methylbenzoic acid 
• 950915-10-3 4-chloro-2-methyl-3-nitro-benzoic acid 
• 74-11-3 para-chlorobenzoic acid 

Downstream Products

• 863885-79-4 methyl 2-methyl-4-(methylamino)-5-nitrobenzoate 
• 390816-48-5 4-cyclohexylamino-2-methyl-5-nitrobenzoic acid methyl ester 
• 390816-49-6 4-cyclohexylamino-2-methyl-3-nitrobenzoic acid methyl ester 

Relevant articles and documents

Identification of a Benzimidazolecarboxylic Acid Derivative (BAY 1316957) as a Potent and Selective Human Prostaglandin E2 Receptor Subtype 4 (hEP4-R) Antagonist for the Treatment of Endometriosis

The presence and growth of endometrial tissue outside the uterine cavity in endometriosis patients are primarily driven by hormone-dependent and inflammatory processes - the latter being frequently associated with severe, acute, and chronic pelvic pain. T

Viral polymerase inhibitors

An isomer, enantiomer, diastereoisomer, or tautomer of a compound, represented by formula I: wherein R1 is selected from: H, haloalkyl, (C1-6)alkyl, (C2-6)alkenyl, (C3-7)cycloalkyl, (C2-6)alkynyl, (C5-7)cycloalkenyl, 6 or 10-membered aryl, Het all optionally substituted; R2 is selected from (C1-6)alkyl, (C3-7)cycloalkyl, (C6-10)bicycloalkyl, 6- or 10-membered aryl, or Het all optionally substituted; B is N or CR5, wherein R5 is H, halogen, haloalkyl, (C1-6)alkyl, (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; X is N or CR5; D is N or CR5; each of Y1 and Y2 is independently O or S; Z is O, N, or NRz wherein Rz is H, (C1-6)alkyl, (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; R3 and R4 are each independently H, (C1-6)alkyl, first (C3-7)cycloalkyl or 6- or 10-membered aryl, Het (C1-6)alkyl-6- or 10-membered aryl, (C1-6)alkyl-Het; or each R3 and R4 are independently covalently bonded together to form second (C3-7)cycloalkyl, or heterocycle, all optionally substituted; or when Z is N, either R3 or R4 are independently covalently bonded thereto to form a nitrogen-containing heterocycle; R7 is H, (C1-6 alkyl), (C3-7)cycloalkyl or (C1-6)alkyl-(C3-7)cycloalkyl; or R7 is covalently bonded to either of R3 or R4 to form a heterocycle; A is (C1-6) alkyl-CONHR8 wherein R8 is-6- or 10-membered aryl, or Het; or A is a 6- or 10-membered aryl, or Het said aryl or Het being optionally substituted; or a salt or a derivative thereof; such compounds being potent inhibitors of HCV NS5B polymerase.