477199-06-7

Upstream product

• 120-80-9 benzene-1,2-diol 
• 477199-04-5 (S)-1-((1S,2S,4aS,8aS)-2-hydroxy-2,5,5,8a-tetramethyl-decahydronaphthalen-1-yl)ethane-1,2-diol 
• 477199-01-2 (1S,3aS,5aS,9aS,9bS)-1-hydroxy-3a,6,6,9a-tetramethyl-decahydronaphtho[2,1-b]furan-2(3aH)-one 
• 123357-24-4 (1R,2S,4aS,8aS)-2-hydroxy-2,5,5,8a-tetramethyl-decahydronaphthalene-1-carbaldehyde 
• 564-20-5 (3aR)-(+)-sclareolide 
• 30450-17-0 (3aS,5aS,9aS,9bR)-3a,6,6,9a-tetramethyldecahydronaphtho[2,1-b]furan-2(3aH)-one 
• 16047-57-7 (((4-bromo-1,2-phenylene)bis(oxy))bis(methylene))dibenzene 
• 17345-77-6 1-bromo-3,4-dihydroxybenzene 

Relevant academic research and scientific papers

Enantiospecific synthesis of the antituberculosis marine sponge metabolite (+)-puupehenone. The arenol oxidative activation route.

[formula: see text] The total synthesis of the marine sesquiterpene quinone (+)-puupehenone, a promising new antituberculosis agent, was achieved in 10 steps starting from commercially available (+)-sclareolide. The key feature of this synthesis is the construction of the heterocycle via an intramolecular attack of the terpenoid-derived C-8 oxygen function onto an oxidatively activated 1,2-dihydroxyphenyl unit.