477339-13-2Relevant academic research and scientific papers
Enantioselective sulfide oxidation with H2O2: A solid phase and array approach for the optimisation of chiral Schiff base-vanadium catalysts
Pelotier, Béatrice,Anson, Mike S.,Campbell, Ian B.,Macdonald, Simon J. F.,Priem, Ghislaine,Jackson, Richard F. W.
, p. 1055 - 1060 (2002)
Two libraries of chiral Schiff base ligands were synthesised and screened in the vanadium-catalysed oxidation of alkyl aryl sulfides with hydrogen peroxide as terminal oxidant. The vanadium-chiral Schiff base complex 10, readily prepared from 3,5-diiodo-salicylaldehyde and (S)-tert-leucinol, was found to be highly enantioselective. Optically active sulfoxides could thus be obtained in good yields with up to 97% ee.
