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(2E)-N-hydroxy-3-nitrosopent-2-en-2-amine, commonly referred to as NHPA, is a nitrosamine derivative characterized by its molecular formula C5H10N2O2. This small molecule features a nitroso group, an amine group, and a double bond, which contribute to its unique chemical properties and reactivity. As a compound of interest in the field of organic chemistry, NHPA has been investigated for its potential biological activities, including its role in DNA adduct formation and its implications in carcinogenicity. Due to its hazardous nature and potential health risks, NHPA must be handled with caution.

4775-86-4

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4775-86-4 Usage

Uses

Used in Organic Synthesis:
NHPA is utilized as a reagent in the synthesis of various organic compounds, taking advantage of its reactive functional groups to facilitate a range of chemical reactions. Its versatility in organic synthesis makes it a valuable tool for creating new molecules with potential applications in different industries.
Used in Research and Development:
In the field of research and development, NHPA is employed to study its potential biological activities. Scientists are particularly interested in understanding its role in the formation of DNA adducts and its carcinogenic properties. This knowledge can contribute to the development of strategies for cancer prevention and treatment.
Used in Industrial Applications:
While the specific industrial applications of NHPA are not explicitly mentioned in the provided materials, its use as a reagent in organic synthesis suggests that it may be involved in the production of chemicals, pharmaceuticals, or other products that require the creation of complex organic molecules.
Used in Safety and Hazard Assessment:
Given its classification as a hazardous substance, NHPA is also used in safety and hazard assessment studies. These studies aim to determine the potential risks associated with its use and to develop guidelines for safe handling, storage, and disposal to minimize health and environmental risks.

Check Digit Verification of cas no

The CAS Registry Mumber 4775-86-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,7 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4775-86:
(6*4)+(5*7)+(4*7)+(3*5)+(2*8)+(1*6)=124
124 % 10 = 4
So 4775-86-4 is a valid CAS Registry Number.

4775-86-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(E)-3-nitrosopent-2-en-2-yl]hydroxylamine

1.2 Other means of identification

Product number -
Other names 2,3-Pentanedione, dioxime

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4775-86-4 SDS

4775-86-4Downstream Products

4775-86-4Relevant academic research and scientific papers

High-Throughput Screening of Earth-Abundant Water Reduction Catalysts toward Photocatalytic Hydrogen Evolution

Motz, Rachel N.,Lopato, Eric M.,Connell, Timothy U.,Bernhard, Stefan

supporting information, p. 774 - 781 (2021/02/05)

Noble-metal photosensitizers and water reduction co-catalysts (WRCs) still present the highest activity in homogeneous photocatalytic hydrogen production. The search for earth-abundant alternatives is usually limited by the time required to screen new catalyst combinations; however, here, we utilize newly designed and developed high-throughput photoreactors for the parallel synthesis of novel WRCs and colorimetric screening of hydrogen evolution. This unique approach allowed rapid optimization of photocatalytic water reduction using the organic photosensitizer Eosin Y and the archetypal cobaloxime WRC [Co(GL1)2pyCl], where GL1 is dimethylglyoxime and py is pyridine. Subsequent combinatorial synthesis generated 646 unique cobalt complexes of the type [Co(LL)2pyCl], where LL is a bidentate ligand, that identified promising new WRC candidates for hydrogen production. Density functional theory (DFT) calculations performed on such cobaloxime derivative complexes demonstrated that reactivity depends on hydride affinity. Alkyl-substituted glyoximes were necessary for hydrogen production and showed increased activity when paired with ligands containing strong hydrogen-bond donors.

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