478165-17-2

Basic information

• Product Name: (4-methoxy-3,6-dioxo-cyclohexa-1,4-dienyl)-acetic acid methyl ester
• CAS NO: 478165-17-2
• Molecular Weight: 210.186
• Mol File: 478165-17-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-methoxy-3,6-dioxo-cyclohexa-1,4-dienyl)-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methoxy-3,6-dioxo-cyclohexa-1,4-dienyl)-acetic acid methyl ester(478165-17-2)
• EPA Substance Registry System: (4-methoxy-3,6-dioxo-cyclohexa-1,4-dienyl)-acetic acid methyl ester(478165-17-2)

Safety Data

• Hazardous Substances Data: 478165-17-2(Hazardous Substances Data)

Upstream product

• 53811-44-2 2,4,5-trimethoxybenzyl chloride 
• 30038-31-4 (2,4,5-trimethoxyphenyl)methanol 
• 20029-76-9 methyl 2,4,5-trimethoxybenzoate 
• 4463-16-5 2,4,5-trimethoxyphenylacetic acid 
• 38444-50-7 2,4,5-trimethoxybenzeneacetonitrile 
• 490-64-2 asaronic acid 
• 2638-15-5 methyl 2-(2,4,5-trimethoxyphenyl)acetate 

Relevant articles and documents

Design, synthesis, and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hydroxyphenylpyruvate dioxygenase

An epoxybenzoquinone, 4-hydroxyphenoxypropionic acid, and 2-hydroxy-3-phenyl-3-butenoic acid derivatives have been designed, synthesized, and evaluated for in vitro inhibition activity against 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) from pig liver by the spectrophotometric enol-borate method. The biological data demonstrated that neither epoxybenzoquinone ester nor 2-hydroxy-3-phenyl-3-butenoic acid is an inhibitor of 4-HPPD. The most potent 4-HPPD inhibitor tested was 3-hydroxy-4-phenyl-2(5H)-furanone with an IC50 value of 0.5 μM, which may serve as a lead compound for further design of more potent 4-HPPD inhibitors.