53811-44-2

Usage

Uses

Used in Pharmaceutical Synthesis:
2,4,5-Trimethoxybenzyl chloride is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Production:
In the agrochemical industry, 2,4,5-Trimethoxybenzyl chloride is utilized as a building block for the creation of effective and safe agrochemicals, enhancing crop protection and yield.
Used in Fragrance Manufacturing:
2,4,5-Trimethoxybenzyl chloride is employed as a raw material in the production of fragrances, contributing to the creation of unique and appealing scents for various applications.
Used in Dye Synthesis:
2,4,5-TRIMETHOXYBENZYL CHLORIDE is used as a precursor in the synthesis of dyes, enabling the development of a wide range of colorants for different industries, including textiles, plastics, and printing.
Used in Fine Chemicals Production:
2,4,5-Trimethoxybenzyl chloride is utilized in the manufacturing of fine chemicals, which are essential for various applications in research, pharmaceuticals, and other specialized industries.

InChI:InChI=1/C10H13ClO3/c1-12-8-5-10(14-3)9(13-2)4-7(8)6-11/h4-5H,6H2,1-3H3

Upstream product

• 30038-31-4 (2,4,5-trimethoxyphenyl)methanol 
• 20029-76-9 methyl 2,4,5-trimethoxybenzoate 
• 4460-86-0 asaraldehyde 
• 490-64-2 asaronic acid 

Downstream Products

• 38444-50-7 2,4,5-trimethoxybenzeneacetonitrile 
• 111596-41-9 3-(4,5-dimethoxy-2-vinylphenyl)-5,7,8-trimethoxy-2-methyl-isoquinolin-1(2H)-one 
• 111596-44-2 3-(4,5-dimethoxy-2-vinylphenyl)-5,7-dimrthoxy-2-methyl-isoquinolin-1(2H)-one 
• 111596-38-4 1,2,3,4-tetrahydro-6,7-dimethoxy-1-(2,4,5-trimethoxybenzyl)isoquinoline 
• 111619-16-0 1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-(2,4,5-trimethoxybenzyl)isoquinoline 
• 111596-43-1 6,7-Dimethoxy-1-(2,4,5-trimethoxy-benzyl)-3,4-dihydro-1H-isoquinoline-2-carbaldehyde 
• 75499-78-4 N-β-<(3,4-dimethoxyphenyl)ethyl>-2,4,5-trimethoxyphenylacetamide 
• 1064198-04-4 6-benzyloxy-7-methoxy-2-(2,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline 
• 478165-17-2 (4-methoxy-3,6-dioxo-cyclohexa-1,4-dienyl)-acetic acid methyl ester 
• 4463-16-5 2,4,5-trimethoxyphenylacetic acid 
• 2638-15-5 methyl 2-(2,4,5-trimethoxyphenyl)acetate 

Relevant academic research and scientific papers

Design, synthesis, and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hydroxyphenylpyruvate dioxygenase

An epoxybenzoquinone, 4-hydroxyphenoxypropionic acid, and 2-hydroxy-3-phenyl-3-butenoic acid derivatives have been designed, synthesized, and evaluated for in vitro inhibition activity against 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) from pig liver by the spectrophotometric enol-borate method. The biological data demonstrated that neither epoxybenzoquinone ester nor 2-hydroxy-3-phenyl-3-butenoic acid is an inhibitor of 4-HPPD. The most potent 4-HPPD inhibitor tested was 3-hydroxy-4-phenyl-2(5H)-furanone with an IC50 value of 0.5 μM, which may serve as a lead compound for further design of more potent 4-HPPD inhibitors.

Chemical Transformation of Protoberberines. Part 10. A Novel Synthesis of Sanguilutine and Dihydrosanguilutine, fully Aromatised 2,3,7,8,10-Pentaoxygenated Benzophenanthridine Alkaloids

2,3,7,8,10-Pentaoxygenated benzophenanthridine alkaloids, sanguilutine (1) and dihydrosanguilutine (2), were efficiently synthesized from the corresponding 2,3,9,10,12-pentamethoxyprotoberberine (8) through a regioselective C(6)-N bond cleavage, followed by recombination between the original C(6) and C(13) positions of compound (8) according to a biomimetic route.