4786-52-1

Basic information

• Product Name: Ethyl 4-hydroxypyrimidine-5-carboxylate
• Synonyms: 6-Hydroxypyrimidine-5-carboxylic acid ethyl ester;Ethyl 6-oxo-1,6-dihydropyrimidine-5-carboxylate LR;4-hydroxy-5-pyrimidinecarboxylicaciethylester;ETHYL 4-HYDROXYPYRIMIDINE-5-CARBOXYLATE;6-OXO-1,6-DIHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER;4-HYDROXY-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER;5-Pyrimidinecarboxylic acid, 1,4-dihydro-4-oxo-, ethyl ester;Ethyl 1,4-dihydro-4-oxo-5-pyrimidinecarboxylate
• CAS NO: 4786-52-1
• Molecular Formula: C₇H₈N₂O₃
• Molecular Weight: 168.15
• Product Categories: pharmacetical;Heterocycle-Pyrimidine series;CMLLYL
• Mol File: 4786-52-1.mol
• Article Data: 9

Chemical Properties

• Melting Point: 185-186 °C
• Boiling Point: 270.6 °C at 760 mmHg
• Flash Point: 117.4 °C
• Appearance: /
• Density: 1.33 g/cm³
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 7.70±0.40(Predicted)
• CAS DataBase Reference: Ethyl 4-hydroxypyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4-hydroxypyrimidine-5-carboxylate(4786-52-1)
• EPA Substance Registry System: Ethyl 4-hydroxypyrimidine-5-carboxylate(4786-52-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 4786-52-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H8N2O3/c1-2-12-7(11)5-3-8-4-9-6(5)10/h3-4H,2H2,1H3,(H,8,9,10)

Upstream product

• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 3473-63-0 formamidine acetic acid 
• 6313-33-3 formamidine hydrochloride 
• 51953-17-4 Pyrimidin-4-ol 
• 105-53-3 diethyl malonate 
• 38026-46-9 ethyl 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxilate 
• 4774-33-8 tris(formylamino)methane 

Downstream Products

• 1328624-09-4 ethyl 4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)pyrimidine-5-carboxylate 
• 1352805-02-7 4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)pyrimidine-5-carboxylic acid 
• 1328624-10-7 methyl 2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)pyrimidin-5-carbnyl)amino)-3-hydroxypropanoate 
• 1315469-71-6 ethyl 4-(2,5-dichlorophenoxy)pyrimidine-5-carboxylate 
• 1315469-70-5 4-(2,5-dichlorophenoxy)pyrimidine-5-carboxylate 
• 1415407-12-3 C₂₀H₁₈Cl₂N₄O₂ 
• 1415407-13-4 C₁₉H₁₅Cl₂N₃O₂ 
• 1415407-14-5 C₁₈H₁₃Cl₂N₃O₂ 
• 1415407-15-6 C₁₉H₁₅Cl₂N₃O₃ 
• 1415407-16-7 C₁₈H₁₃Cl₂N₃O₂ 
• 1415407-17-8 C₂₀H₁₇Cl₂N₃O₂ 
• 1315469-37-4 [4-(2,5-dichloro-phenoxy)-pyrimidin-5-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone 
• 1415407-19-0 C₂₁H₁₈Cl₂N₄O₂ 
• 1415407-20-3 C₂₂H₂₀Cl₂N₄O₂ 

Relevant articles and documents

HETEROCYCLIC COMPOUND AND USE THEREOF

Provided is a heterocyclic compound that can have an antagonistic action on an NMD A receptor containing the NR2B subunit and that is expected to be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like. A compound represented by the formula (I), wherein each symbol is as defined in the DESCRIPTION, or a salt thereof.

NOVEL PYRIMIDINE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS

The present invention provides a novel pyrimidine derivative or pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising same, which can effectively inhibit the growth of cancer cells induced by the overexpression of EGFR incl

NEUROPEPTIDE Y4 RECEPTOR AGONISTS

This invention provides peptides that act as selective NPY4 receptor agonists in vitro and are efficacious in vivo to reduce food intake. The invention is a peptide selected from a specific group of derivatized PP-related peptides, or functional equivalents thereof. The invention is also directed to a method of treating a metabolic disease in a mammal comprising administering a therapeutically effective amount of the peptides to said mammal to reduce food intake and body weight.