478645-89-5Relevant articles and documents
Method for synthesizing amide compounds by using N-Boc amide as substrate
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Paragraph 0220-0228, (2020/01/12)
The invention relates to a method for synthesizing amide compounds by using N-Boc amide as a substrate. According to the method, N-Boc amide and various amine compounds are subjected to an intermolecular nucleophilic substitution reaction in an organic solvent so as to efficiently prepare various amide compounds. The method has the advantages of mild reaction conditions, simple and convenient operation, high yield and good functional group compatibility.