55306-69-9

Upstream product

• 478645-89-5 C₁₇H₂₄N₂O₃ 
• 5221-40-9 N-(3-pyridinyl)benzamide 

Downstream Products

• 396730-17-9 N-(phenylmethyl)-3-piperidinamine 
• 1016538-77-4 C₁₅H₂₀N₂O₂ 
• 1016538-76-3 C₁₄H₁₈N₂O₂ 
• 668270-12-0 Linagliptin 
• 334618-23-4 3-(R)-aminopiperidine dihydrochloride 
• 1062136-14-4 (R)-N-(piperidin-3-yl)benzamide 
• 573718-00-0 3-(benzylamino)-1-piperidinecarboxylic acid 

Relevant academic research and scientific papers

Compound I and (R)- 3 - amino piperidine hydrochloride II, its preparation method and its application in the synthesis of advantage geleg sandbank

The invention discloses a preparation method of 3-aminopiperidine and its derivative with optical activity and an application of the compound and its derivative in synthesis of a dipeptidyl peptidase-IV inhibitor Linagliptin. According to the preparation

Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers

A series of 2-oxopiperazine, 4-aminomethyl-, 3-amino- and 3-aminomethylpiperidine analogues of DM235 (sunifiram) and MN19 (sapunifiram), two previously reported potent cognition-enhancers, have been synthesized and tested in the mouse passive-avoidance test. The compounds display minimal effective doses in the range 0.3-10 mg/kg. Although the new substances do not show improved activity when compared to the parent compounds, some useful information has been obtained to understand structure-activity relationships. In addition, the 3-aminopiperidine moiety appears to be a promising scaffold to synthesize new drugs endowed with cognition-enhancing activity.

Azabicyclic compounds, preparation thereof and use as medicines, in particular as antibacterial agents

The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a process for the preparation of these compounds as well as their use as medicaments, in particular as anti-bacterial agents.