478800-17-8Relevant articles and documents
Total synthesis of (-)-histrionicotoxin 285A and (-)- perhydrohistrionicotoxin
Macdonald, James M.,Horsley, Helen T.,Ryan, John H.,Saubern, Simon,Holmes, Andrew B.
supporting information; experimental part, p. 4227 - 4229 (2009/06/06)
(Chemical Equation Presented) Starting from commercially available (S)-glycidol, and via a common intermediate, the total synthesis of (-)-histrionicotoxin 285A and (-)-perhydrohistrionicotoxin has been achieved. Key to this synthesis was the efficient co
Oxabicyclo[3.2.1]oct-6-enes as templates for the stereoselective synthesis of polypropionates: Total synthesis of callystatin a and C19-epi-callystatin A
Lautens, Mark,Stammers, Timothy A.
, p. 1993 - 2012 (2007/10/03)
The total synthesis of the polyketide natural product callystatin A and its novel analog C19-epi-callystatin A is described. Our strategy features the use of an enantiomerically pure oxabicyclo[3.2.1]oct-6-ene as a template for the stereocontrolled preparation of the C15-C21 polypropionate region.