478800-46-3

Upstream product

• 478800-18-9 (Z)-(2R)-6-(tert-butyldiphenylsilanyloxy)hex-2-ene-1,5-diol 
• 107033-46-5 (R)-(tert-butyldiphenylsilyloxy)methyloxirane 
• 127793-64-0 (R)-1-O-(tert-butyldiphenylsilyl)-4-penten-1,2-diol 
• 445289-97-4 (R)-1-((tert-butyldiphenylsilyl)oxy)pent-4-en-2-yl acrylate 
• 206651-83-4 (R)-6-(((tert-butyldiphenylsilyl)oxy)methyl)-5,6-dihydro-2H-pyran-2-one 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 478800-17-8 (2R)-1-(tert-butyldiphenylsilanyloxy)-6-(tetrahydropyran-2-yloxy)hex-4-yn-2-ol 
• 478800-45-2 (2R)-1-tert-butyldiphenylsilyloxy-hex-4-yne-2,6-diol 

Downstream Products

• 343981-88-4 tert-butyldiphenyl (((2R,6R)-6-isopropoxy-3,6-dihydro-2H-pyran-2-yl)methoxy)silane 
• 410523-53-4 (2'R,6'R,1E,3Z,5R)-(+)-7-tert-butyldiphenylsilyloxy-1-(5',6'-dihydro-2'H-2'-isopropoxypyran-6'-yl)-3-ethyl-5-methylhepta-1,3-diene 

Relevant academic research and scientific papers

Stereoselective synthesis of the C1-C12 subunit of (-)-callystatin A

A stereoselective synthesis of the C1-C12 fragment of callystatin A is disclosed. The two stereocenters at C5 and C10 were created by an organocatalytic reaction and a diastereoselective alkylation, respectively. The trisubstituted double bond was introdu

Oxabicyclo[3.2.1]oct-6-enes as templates for the stereoselective synthesis of polypropionates: Total synthesis of callystatin a and C19-epi-callystatin A

The total synthesis of the polyketide natural product callystatin A and its novel analog C19-epi-callystatin A is described. Our strategy features the use of an enantiomerically pure oxabicyclo[3.2.1]oct-6-ene as a template for the stereocontrolled preparation of the C15-C21 polypropionate region.