480-65-9

Basic information

• Product Name: ISODEHYDROACETIC ACID
• Synonyms: TIMTEC-BB SBB000157;ISODEHYDRACETIC ACID;ISODEHYDROACETIC ACID;IFLAB-BB F0918-7095;4,6-DIMETHYL-2-OXO-2H-PYRAN-5-CARBOXYLIC ACID;5-CARBOXY-4,6-DIMETHYL-2-PYRONE;AKOS AUF02046;2,4-DIMETHYL-6-OXO-6H-PYRAN-3-CARBOXYLIC ACID
• CAS NO: 480-65-9
• Molecular Formula: C₈H₈O₄
• Molecular Weight: 168.15
• EINECS: 207-554-4
• Product Categories: C8;Carbonyl Compounds;Carboxylic Acids
• Mol File: 480-65-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 154-156 °C
• Boiling Point: 219.79°C (rough estimate)
• Flash Point: 125.8 °C
• Appearance: /
• Density: 1.1456 (rough estimate)
• Vapor Pressure: 0.000215mmHg at 25°C
• Refractive Index: 1.4530 (estimate)
• CAS DataBase Reference: ISODEHYDROACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: ISODEHYDROACETIC ACID(480-65-9)
• EPA Substance Registry System: ISODEHYDROACETIC ACID(480-65-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 24/25-26
• Hazardous Substances Data: 480-65-9(Hazardous Substances Data)

Usage

Chemical Properties

WHITE CRYSTALLINE POWDER

InChI:InChI=1/C8H8O4/c1-4-3-6(9)12-5(2)7(4)8(10)11/h3H,1-2H3,(H,10,11)/p-1

Upstream product

• 141-97-9 ethyl acetoacetate 
• 105-45-3 acetoacetic acid methyl ester 
• 41264-06-6 methyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate 
• 7664-93-9 sulfuric acid 
• 3385-34-0 ethyl isodehydroacetate 

Downstream Products

• 675-09-2 4,6-Dimethyl-2-pyron 
• 141-79-7 4-methyl-pent-3-en-2-one 
• 124-38-9 carbon dioxide 
• 1448807-51-9 N-[4-(3,4-dimethoxyphenyl)-2-thienyl]-2,4-dimethyl-6-oxopyran-3-carboxamide 
• 1310924-00-5 2,4-dimethyl-6-oxo-1-propylamino-1,6-dihydro-pyridine-3-carboxylic acid [(S)-cyclobutyl-(3-fluoro-phenyl)-methyl]-amide 
• 1310923-97-7 1-amino-2,4-dimethyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid [(S)-cyclobutyl-(3-fluoro-phenyl)-methyl]-amide 
• 1310923-95-5 2,4-dimethyl-6-oxo-6H-pyran-3-carboxylic acid [(S)-cyclobutyl-(3-fluoro-phenyl)-methyl]-amide 
• 7470-47-5 2,4-dimethyl-6-oxo-6H-pyran-3-carboxylic acid propyl ester 
• 41264-06-6 methyl 4,6-dimethyl-2-oxo-2H-pyran-5-carboxylate 
• 76877-04-8 1-Amino-2,4-dimethyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid 
• 372-42-9 3-methylpent-2-enedioic acid 
• 76876-99-8 1-(1-naphthylamino)-5-carboxy-4,6-dimethyl-2(1H)-pyridone 
• 76876-98-7 1-(2-chlorophenylamino)-5-carboxy-4,6-dimethyl-2(1H)-pyridone 
• 76877-02-6 1-(4-methoxyphenylamino)-5-carboxy-4,6-dimethyl-2(1H)-pyridone 

Relevant articles and documents

COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS

The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising: (a) a polymer backbone that may be obtained by reaction: of a polyol comprising 3 to 6 hydroxyl groups;of a monocarboxylic acid containing 6 to 32 carbon atoms;of a polycarboxylic acid comprising at least two carboxylic groups COOH, and/or of a cyclic anhydride such as a polycarboxylic acid and/or of a lactone comprising at least one carboxylic group COOH; and(b) at least one junction group linked to the said polymer backbone and capable of establishing H bonds with one or more partner junction groups, each pairing of a junction group involving at least three H (hydrogen) bonds. The patent application also concerns a cosmetic treatment process using the said composition.

An improved synthesis of a mixture of diethyl (Z)- and (E)-3-methylglutaconates from ethyl acetoacetate

A simple, efficient two-step synthesis of a mixture of diethyl (Z)- and (E)-3-methylglutaconates from isodehydroacetic acid in 83% yield is described. On the basis of this synthesis an improved procedure for the preparation of a mixture of (Z)- and (E)-3-methylglutaconic acids from ethyl acetoacetate in 44% overall yield was elaborated.