480453-86-9Relevant academic research and scientific papers
Synthesis and SAR studies of potent imidazopyridine anticoccidial agents
Liang, Gui-Bai,Qian, Xiaoxia,Feng, Dennis,Fisher, Michael,Brown, Christine M.,Gurnett, Anne,Leavitt, Penny Sue,Liberator, Paul A.,Misura, Andrew S.,Tamas, Tamas,Schmatz, Dennis M.,Wyvratt, Matthew,Biftu, Tesfaye
, p. 3558 - 3561 (2008/02/13)
Diaryl imidazo[1,2-a]pyridine derivatives, such as 6a and 7i, have been synthesized and found to be potent inhibitors of parasite PKG activity. The most potent compounds are the 7-isopropylaminomethyl analog 6a and 2-isopropylamino analog 7i. These compounds are also fully active in in vivo assay as anticoccidial agents at 25 ppm in feed.
