480457-97-4

Upstream product

• 480453-78-9 [2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]methanol 
• 695-34-1 2-Amino-4-methylpyridine 
• 403-33-8 methyl 4-flurobenzoate 
• 266358-16-1 2-bromo-1-(4-fluorophenyl)-2-(2-methylsulfanylpyrimidin-4-yl)ethanone 
• 217661-99-9 1-(4-fluorophenyl)-2-(2-methylsulphanylpyrimidin-4-yl)-1-ethanone 
• 105250-17-7 2-amino-4-hydroxymethylpyridine 
• 54221-95-3 2-(acetylamino)isonicotinic acid 
• 13362-30-6 2-amino-4-ethoxycarbonyl-pyridine 
• 5327-32-2 2-acetylamino-4-methylpyridine 
• 14001-63-9 2-methylthio-4-methylpyrimidine 

Downstream Products

• 918955-22-3 [2-(4-fluoro-phenyl)-3-(2-methylamino-pyrimidin-4-yl)-imidazo[1,2-a]pyridin-7-yl]-methanol 
• 918955-25-6 [3-(2-benzyloxy-pyrimidin-4-yl)-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridin-7-yl]-methanol 
• 480453-84-7 C₂₃H₂₄FN₅O 
• 480456-00-6 C₂₂H₂₂FN₅O 
• 480456-65-3 C₂₁H₂₀FN₅O 
• 480456-08-4 C₂₄H₁₈FN₅O 
• 918955-31-4 methanesulfonic acid 2-(4-fluoro-phenyl)-3-[2-(1-phenyl-ethylamino)-pyrimidin-4-yl]-imidazo[1,2-a]pyridin-7-ylmethyl ester 
• 918955-32-5 methanesulfonic acid 3-[2-(benzyl-methyl-amino)-pyrimidin-4-yl]-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridin-7-ylmethyl ester 
• 918955-33-6 methanesulfonic acid 3-(2-benzyloxy-pyrimidin-4-yl)-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridin-7-ylmethyl ester 
• 918955-29-0 methanesulfonic acid 2-(4-fluoro-phenyl)-3-(2-methylamino-pyrimidin-4-yl)-imidazo[1,2-a]pyridin-7-ylmethyl ester 
• 918955-34-7 methanesulfonic acid 2-(4-fluoro-phenyl)-3-(2-methoxy-pyrimidin-4-yl)-imidazo[1,2-a]pyridin-7-ylmethyl ester 

Relevant academic research and scientific papers

Synthesis and biological activity of imidazopyridine anticoccidial agents: Part II

Coccidiosis is the major cause of morbidity and mortality in the poultry industry. Protozoan parasites of the genus Eimeria invade the intestinal lining of the avian host causing tissue pathology, poor weight gain, and in some cases mortality. Resistance

Synthesis and SAR of 2-(4-fluorophenyl)-3-pyrimidin-4-ylimidazo[1,2-a]pyridine derivatives as anticoccidial agents

Compounds 10a-10d and 10i are very potent inhibitors of Eimeria tenella cGMP-dependent protein kinase (0.081-0.32 nM) and are very efficacious antiparasitic agents in vivo when administered to chickens at 12.5-25 ppm levels in the feed.