481063-40-5

Upstream product

• 63-29-6 D-glucurono-6,3-lactone 
• 183509-18-4 (3aR,3bS,5S,6S,6aS,7aR)-6-(tert-Butyl-dimethyl-silanyloxy)-2,2-dimethyl-5-phenyl-hexahydro-furo[2',3':4,5]furo[2,3-d][1,3]dioxol-5-ol 
• 3067-56-9 D-glucurono-3,6-lactone acetonide 
• 126214-81-1 5-O-tert-butyldimethylsilyl-1,2-O-isopropylidene-α-D glucofuraurono-6,3-lactone 
• 481063-68-7 tert-Butyl-((3aR,3bS,5S,6R,6aS,7aR)-2,2-dimethyl-5-phenyl-hexahydro-furo[2',3':4,5]furo[2,3-d][1,3]dioxol-6-yloxy)-dimethyl-silane 

Downstream Products

• 481066-71-1 (3aR,3bS,5S,6S,6aR,7aR)-2,2-Dimethyl-5-phenyl-hexahydro-furo[2',3':4,5]furo[2,3-d][1,3]dioxol-6-ol 
• 481063-61-0 (R)-((2S,3R,4R,5S)-4-Benzyloxy-3-hydroxy-5-phenyl-tetrahydro-furan-2-yl)-hydroxy-acetaldehyde 
• 481063-42-7 (S)-1-((2R,3R,4R,5S)-4-Benzyloxy-3-hydroxy-5-phenyl-tetrahydro-furan-2-yl)-ethane-1,2-diol 
• 481066-72-2 (3aR,3bS,5S,6S,6aR,7aR)-6-Benzyloxy-2,2-dimethyl-5-phenyl-hexahydro-furo[2',3':4,5]furo[2,3-d][1,3]dioxole 
• 481063-78-9 (2S,3R,4R,5S)-4-Benzyloxy-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-5-phenyl-tetrahydro-furan-3-ol 
• 481063-44-9 (S)-1-((2R,3R,4S,5S)-3,4-Bis-benzyloxy-5-phenyl-tetrahydro-furan-2-yl)-ethane-1,2-diol 
• 481063-81-4 (S)-4-((2R,3R,4S,5S)-3,4-Bis-benzyloxy-5-phenyl-tetrahydro-furan-2-yl)-2,2-dimethyl-[1,3]dioxolane 

Relevant academic research and scientific papers

First practical asymmetric synthesis of a new tetrasubstituted tetrahydrofuran, (-)-goniothalesdiol

An efficient and practical strategy has been developed for the construction of the antipode of 3,4-dihydroxy-2,5-disubstituted tetrahydrofuran, goniothalesdiol, isolated from the bark of the Malaysian tree. The synthetic process is based on the convenient manipulation via Lewis acid-induced deoxygenation of the highly functionalized lactone derived from D-glucuronolactone.