481066-72-2Relevant articles and documents
First practical asymmetric synthesis of a new tetrasubstituted tetrahydrofuran, (-)-goniothalesdiol
Yoda, Hidemi,Nakaseko, Yuka,Takabe, Kunihiko
, p. 1532 - 1534 (2007/10/03)
An efficient and practical strategy has been developed for the construction of the antipode of 3,4-dihydroxy-2,5-disubstituted tetrahydrofuran, goniothalesdiol, isolated from the bark of the Malaysian tree. The synthetic process is based on the convenient manipulation via Lewis acid-induced deoxygenation of the highly functionalized lactone derived from D-glucuronolactone.