48144-44-1

Basic information

• Product Name: 1-(3-chlorophenyl)biguanide
• Synonyms: Biguanide,1-(m-chlorophenyl)- (6CI); m-Chlorophenylbiguanide; mCPBG
• CAS NO: 48144-44-1
• Molecular Formula: C₈H₁₀ClN₅
• Molecular Weight: 211.66
• Mol File: 48144-44-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(3-chlorophenyl)biguanide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-chlorophenyl)biguanide(48144-44-1)
• EPA Substance Registry System: 1-(3-chlorophenyl)biguanide(48144-44-1)

Safety Data

• Hazardous Substances Data: 48144-44-1(Hazardous Substances Data)

Usage

General Description

1-(3-chlorophenyl)biguanide is a chemical compound with the formula C8H11ClN5. It is commonly known as chlorhexidine, and is widely used as an antiseptic and disinfectant. It is effective against a wide range of bacteria, viruses, and fungi, and is commonly used in healthcare settings to disinfect skin and surgical instruments. Chlorhexidine works by disrupting the cell membranes of microorganisms, leading to their death. It is also commonly found in oral care products such as mouthwashes and toothpastes due to its ability to reduce plaque and gingivitis. However, it should be used with caution as prolonged use can lead to resistance of microorganisms and allergic reactions in some individuals.

Upstream product

• 127099-85-8 dicyandiamide 
• 108-42-9 3-chloro-aniline 
• 141-85-5 3-chloroaniline hydrochloride 
• 127099-85-8 N-Cyanoguanidine 

Downstream Products

• 718-43-4 R 37 
• 1381874-46-9 2-(3-chlorophenylamino)-4,8-dimethyl-6H-pyrimido[1,2-a]-[1,3,5]triazin-6-one 
• 52632-39-0 N-carbamimidoyl-N'-(3-chloro-phenyl)-urea 

Relevant articles and documents

Novel compounds having treatment of immune diseases and use therof

The present invention relates to a novel compound capable of effectively treating and preventing immune disease and to a use thereof. The novel compound of the present invention suppresses the production of inflammatory cytokines and increases activities of regulatory T cells having immune regulatory ability. In addition, the compound of the present invention controls over an excessive immune response by inhibiting the production of autoantibodies and differentiation of osteoclasts, thereby being able to be used for treating immune diseases induced by regulatory anomalies of various immune response such as autoimmune disease, inflammatory diseases, and transplant rejection.(a) Cell toxicity effect control(MTT assay)(AA) Normal mouse cell(b) Autoantibody production immune reaction control(c) Inflammatory cytokine production control(d) Inflammatory gene expression controlCOPYRIGHT KIPO 2016