481632-29-5Relevant academic research and scientific papers
Linking bisphosphonates to the free amino groups in fluoroquinolones: Preparation of osteotropic prodrugs for the prevention of osteomyelitis
Houghton, Tom J.,Tanaka, Kelly S. E.,Kang, Ting,Dietrich, Evelyne,Lafontaine, Yanick,Delorme, Daniel,Ferreira, Sandra S.,Viens, Frederic,Arhin, Francis F.,Sarmiento, Ingrid,Lehoux, Dario,Fadhil, Ibtihal,Laquerre, Karine,Liu, Jing,Ostiguy, Valérie,Poirier, Hugo,Moeck, Gregory,Parr Jr., Thomas R.,Far, Adel Rafai
experimental part, p. 6955 - 6969 (2009/11/30)
Osteomyelitis is an infection located in bone and a notoriously difficult disease to manage, requiring frequent and heavy doses of systemically administered antibiotics. Targeting antibiotics to the bone after systemic administration may provide both grea
Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections
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Page/Page column 90, (2008/12/09)
The present invention relates to phosphonated fluoroquinolones, antibacterial analogs thereof, and methods of using such compounds. These compounds are useful as antibiotics for prevention and/or the treatment of bone and joint infections, especially for the prevention and/or treatment of osteomyelitis.
2-(2,6-disubstituted phenyl)-4-aryl-5-alkyl-1,3-oxazoline compounds
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, (2008/06/13)
Oxazoline compounds having a 2,6-disubstituted-phenyl group in the 2-position, an aryl or heteroaryl group in the 4-position and an alkyl group in the 5-position are effective in controlling aphids, insects and mites.
