481648-61-7Relevant academic research and scientific papers
Synthesis and spectral characterization of novel 1,3,4-oxadiazole and 1,2,4-triazole derivatives: Synthesis for potential pharmacological activities
Faidallah, Hassan M.,Sharshira, Essam M.,Basaif, Salem A.,A-Ba-Oum, Abd El-Kader
, p. 67 - 79 (2002)
Oxadiazole derivatives (3a,b) and (4a,b) were obtained in a good yield by the reaction of the benzylidene derivatives (2a,b) with acetic anhydride and yellow mercuric oxide respectively. Cyclodesulfurization of the thiosemicarbazide derivatives (5a-c) with yellow mercuric oxide afforded the oxadiazoles (7a-c). On the other hand, reaction of (5a-c) with sodium hydroxide gave the triazoles (6a-c). The structures of the isolated products were fully determined by spectral methods.
