481704-72-7Relevant academic research and scientific papers
An efficient synthesis of thalifoline
Wang, You-Chu,Georghiou, Paris E.
, p. 2187 - 2190 (2002)
An efficient multi-step approach for the synthesis of the isoquinolin-1-one alkaloid thalifoline (1) is described. The key intermediate carbamate 8a underwent a modified Bischler-Napieralski-type cyclization using Banwell's Tf2O/DMAP conditions to form the lactam 9a under mild conditions and in excellent yield.
