482656-48-4Relevant articles and documents
NOVEL ANTIDIABETIC COMPOUNDS
-
Page/Page column 72-73, (2010/11/29)
The present invention provides novel compounds of the general formula (I), wherein the symbols are same as described in specification, their pharmaceutically acceptable salts, their tautomeric forms, their stereoisomers, pharmaceutical compositions containing them, to process and intermediates for the preparation of the above said compounds, having the utility of these compounds in medicine and to methods for their therapeutic use, and their use in the treatment of diabetes and related diseases.
Efficient synthesis of antihyperglycemic (S)-alpha-aryloxy-beta-phenylpropionic acid using a bifunctional asymmetric catalyst.
Takamura, Makoto,Yanagisawa, Hiroaki,Kanai, Motomu,Shibasaki, Masakatsu
, p. 1118 - 1121 (2007/10/03)
Antihyperglycemic (S)-alpha-aryloxy-beta-phenylpropionic acid was prepared using catalytic asymmetric cyanosilylation as a key reaction to construct alpha-oxycarboxylic acid moiety.