4833-50-5

Upstream product

• 151-50-8 potassium cyanide 
• 108-94-1 cyclohexanone 
• 931-97-5 1-hydroxy-1-cyclohexanecarbonitrile 
• 773837-37-9 sodium cyanide 
• 5496-10-6 1-amino-1-cyanocyclohexane 
• 67-64-1 acetone 
• 111696-97-0 2-aminoadamantane-2-carbonitrile hydrochloride 
• 50846-38-3 1-aminocyclohexane carbonitrile hydrochloride 

Downstream Products

• 16256-16-9 α,α-Pentamethylen-α-amino-thioessigsaeure-amid 
• 57232-06-1 14-p-tolylcarbamoyl-7,14-diazadispiro[5.1.5.2]pentadecane-15-thione 

Relevant academic research and scientific papers

Thioimidazolidine derivatives as oil-soluble additives for lubricating oils

A compound of formula I: ???wherein W represents O, S-A2, or two groups, R3 and R4; bonds a and b are single or double bonds, provided that one of a and b is a single bond and the other is a double bond; c is a single or double bond, and d is a single bond, double bond, or two single bonds, provided that d is a single bond when c is a double bond, d is not a single bond when c is a single bond, and W is R3 and R4 when d is two single bonds; ???A1, A2, B1 and B2 are independently hydrogen, alkyl, alkenyl, aralkyl or one of the groups depicted in Scheme 1: useful as oil-soluble additives for lubricating oils.

Oil-soluble additive compositions for lubricating oils comprising imidazolidine thione

An oil-soluble lubricant additive composition comprising:(a) at least one compound of formula I: wherein R1, R2, R3 and R4 are independently hydrogen, alkyl, alkenyl, aryl or aralkyl; or R1 and R2, or R3 and R4, combine with the carbon atom to which they are attached to form an alkyl or alkenyl ring; and (b) an acid having the formula RCO2H, wherein R is C1-C25 alkyl, C2-C25 alkenyl, C2-C25 alkynyl, C5-C25 aryl or C5-C25 aralkyl.

Preparation of α-aminothioamides from aldehydes

The conversion of aldehydes into α-aminonitriles and thence into imidazolidin-4-thiones has been studied.Hydrolysis of the appropriate imidazolidin-4-thiones gave thioamides of nine naturally occuring α-amino acids.The possible pre-biotic significance of these compounds is discussed.

Assisted hydrolysis of the nitrile group of 2-aminoadamantane-2-carbonitrile

Attempts to hydrolyse the nitrile group of 2-aminoadamantane-2-carbonitrile by mineral acid or alkali have been unsuccessful.However, treatment of the aminonitrile with benzaldehyde in alkaline solution gives the benzal derivative of the α-aminoamide, redily hydrolysed to the α-aminoamide.Alternatively, benzoylation of the amino group followed by acid hydrolysis gives successively the α-benzamido acid and the α-amino acid.Possible mechanisms for these facilitated hydrolyses are advanced.