4840-91-9

Basic information

• Product Name: 2-IODOSTYRENE
• Synonyms: 2-IODOSTYRENE;1-IODO-2-VINYL-BENZENE
• CAS NO: 4840-91-9
• Molecular Formula: C₈H₇I
• Molecular Weight: 230.05
• Product Categories: monomer
• Mol File: 4840-91-9.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 88-90 °C(Press: 3 Torr)
• Appearance: /
• Density: 1.6734 g/cm3
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-IODOSTYRENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODOSTYRENE(4840-91-9)
• EPA Substance Registry System: 2-IODOSTYRENE(4840-91-9)

Safety Data

• Hazardous Substances Data: 4840-91-9(Hazardous Substances Data)

Usage

General Description

2-Iodostyrene, also known as 1-iodo-2-phenylethylene, is a chemical compound with the molecular formula C8H7I. It is a derivative of styrene, containing an iodine atom attached to the benzene ring. 2-Iodostyrene is a versatile building block in organic synthesis, commonly used in the preparation of pharmaceuticals, agrochemicals, and other fine chemicals. It can undergo various chemical reactions, such as palladium-catalyzed cross-coupling reactions, to form a wide range of functionalized products. The compound is also used in the production of polymers and materials with specific properties, making it an important intermediate in the chemical industry. Additionally, 2-Iodostyrene is considered a hazardous substance and should be handled and stored with care in a controlled environment.

Upstream product

• 122752-70-9 2-iodo-α-methyl-benzenemethanol 
• 26260-02-6 2-iodobenzaldehyde 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 609-67-6 2-Iodobenzoyl chloride 
• 111-34-2 -butyl vinyl ether 
• 591-51-5 phenyllithium 
• 88-67-5 2-Iodobenzoic acid 
• 105952-36-1 1-iodo-2-(2-iodoethyl)-benzene 
• 50-00-0 formaldehyd 
• 5159-41-1 2-iodobenzyl alcohol 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 2039-88-5 2-bromostyrene 
• 6919-61-5 N-methoxy-N-methylbenzamide 
• 294190-47-9 2-iodo-N-methoxy-N-methyl-benzamide 

Downstream Products

• 26059-40-5 2-(2-iodophenyl)ethan-1-ol 
• 114657-41-9 1,5-bis(2-iodophenyl)pentan-3-one 
• 480-90-0 1H-inden-1-one 
• 27326-44-9 methyl o-vinylbenzoate 
• 29427-70-1 methyl 3-oxo-2,3-dihydro-1H-indene-1-carboxylate 
• 6908-41-4 4-(methoxycarbonyl)benzyl alcohol 
• 83-33-0 inden-1-one 
• 72525-47-4 2-(2-iodophenyl)oxirane 
• 815577-93-6 1-(2-iodo-pheyl)-hex-5-en-1-ol 
• 88-67-5 2-Iodobenzoic acid 

Relevant articles and documents

Free-radical cyclization approach to polyheterocycles containing pyrrole and pyridine rings

A wide range of derivatives with new pyrido[2,1-a]pyrrolo[3,4-c]isoquinoline skeleton was synthesized by free-radical intramolecular cyclization of o-bromophenyl-substituted pyrrolylpyridinium salts using the (TMS)3SiH/AIBN system. The cyclizat

Weinreb Amide Directed Versatile C?H Bond Functionalization under (η5-Pentamethylcyclopentadienyl)cobalt(III) Catalysis

The (η5-pentamethylcyclopentadienyl)cobalt(III) (Cp*CoIII)-catalyzed C?H bond functionalization of aromatic, heteroaromatic, and α,β-unsaturated Weinreb amides was explored. C?H allylation reactions with the use of allyl carbonate and a perfluoroalkene, oxidative alkenylation reactions with the use of ethyl acrylate, iodination reactions with the use of N-iodosuccinimide, and amidation reactions with the use of dioxazolones were catalyzed by Cp*Co(CO)I2 in the presence of a cationic Ag salt and AgOAc to afford various synthetically useful building blocks. Mechanistic studies of the C?H allylation disclosed that the C?H activation step was rate determining and virtually irreversible.

Diastereoselective C?H Bond Amination for Disubstituted Pyrrolidines

We report herein the improved diastereoselective synthesis of 2,5-disubstituted pyrrolidines from aliphatic azides. Experimental and theoretical studies of the C?H amination reaction mediated by the iron dipyrrinato complex (AdL)FeCl(OEt2) provided a model for diastereoinduction and allowed for systematic variation of the catalyst to enhance selectivity. Among the iron alkoxide and aryloxide catalysts evaluated, the iron phenoxide complex exhibited superior performance towards the generation of syn 2,5-disubstituted pyrrolidines with high diastereoselectivity.