484031-67-6

Basic information

• Product Name: (2,5-dichloro-p-phenylenedioxy)-di-acetic acid
• CAS NO: 484031-67-6
• Molecular Weight: 295.076
• Mol File: 484031-67-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2,5-dichloro-p-phenylenedioxy)-di-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2,5-dichloro-p-phenylenedioxy)-di-acetic acid(484031-67-6)
• EPA Substance Registry System: (2,5-dichloro-p-phenylenedioxy)-di-acetic acid(484031-67-6)

Safety Data

• Hazardous Substances Data: 484031-67-6(Hazardous Substances Data)

Upstream product

• 2245-53-6 2,2'-[1,4-phenylenebis(oxy)]bisacetic acid 
• 64-19-7 acetic acid 
• 824-69-1 2,5-dichloro-1,4-hydroquinone 
• 79-11-8 chloroacetic acid 

Downstream Products

• 484031-61-0 C₁₂H₁₂Cl₂N₈O₂S₂ 
• 144092-24-0 (tetrachloro-p-phenylenedioxy)-di-acetic acid 
• 855931-26-9 (2,5-dichloro-p-phenylenedioxy)-di-acetic acid dimethyl ester 

Relevant articles and documents

New bis-aminomercaptotriazoles and bis-triazolothiadiazoles as possible anticancer agents

A series of bis-phenoxyacetic acids 2 were prepared starting from corresponding unsubstituted/substituted 1,4-quinols 1. The fusion of bis-phenoxyacetic acids 2 with thiocarbohydrazide gave the corresponding bis-[4-amino-5-mercapto-1,2,4-triazol-3-yl-methyleneoxy]phenylenes (3) in a one pot reaction. The reaction of bis-triazoles 3 with various reagents afforded N-bridged heterocycles 4-6 in good yields. The newly synthesised compounds were screened for their anticancer activity against a panel of 60 cell lines derived from seven cancer types namely, lung, colon, melanoma, renal, ovarian, CNS and leukemia. Some of the tested compounds showed promising anticancer properties.