484647-54-3Relevant articles and documents
Total synthesis of desferrisalmycin B
Dong, Li,Roosenberg II, John M.,Miller, Marvin J.
, p. 15001 - 15005 (2007/10/03)
The first total synthesis of a naturally occurring siderophore antibiotic, desferrisalmycin B, is described, and the configuration of the unknown stereocenter is assigned. The synthesis features a synthetic strategy of constructing the novel amino-heptopyranoside component by stereoselective dihydroxylation followed by a Bose-modified Mitsunobu reaction. Through this convergent approach, other members of salmycins should also be synthetically accessible.