484685-96-3

Upstream product

• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 751476-44-5 N-[4-hydroxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-[N,N'-bis(benzyloxycarbonyl)guanidinomethyl]phenylalanine N-methylamide 
• 484685-81-6 N-[4-tert-butyloxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-cyanophenylalanine N-methylamide 
• 484685-84-9 N-[4-hydroxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-cyanophenylalanine N-methylamide 
• 228260-15-9 tert-butyl (S)-(3-(4-cyanophenyl)-1-(methylamino)-1-oxopropan-2-yl)carbamate 
• 152120-55-3 N,N-bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine 

Relevant academic research and scientific papers

Highly water-soluble matrix metalloproteinases inhibitors and their effects in a rat adjuvant-induced arthritis model.

A new series of succinate-based dual inhibitors against matrix metalloproteinases (MMPs) and tumor necrosis factor alpha converting enzyme (TACE) possessing highly-water solubility was designed, synthesized, and evaluated for enzyme inhibition. Incorporat