751476-44-5

Basic information

• Product Name: N-[4-hydroxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-[N,N'-bis(benzyloxycarbonyl)guanidinomethyl]phenylalanine N-methylamide
• Synonyms: N-[4-hydroxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-[N,N'-bis(benzyloxycarbonyl)guanidinomethyl]phenylalanine N-methylamide
• CAS NO: 751476-44-5
• Molecular Weight: 791.945
• Mol File: 751476-44-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[4-hydroxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-[N,N'-bis(benzyloxycarbonyl)guanidinomethyl]phenylalanine N-methylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-hydroxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-[N,N'-bis(benzyloxycarbonyl)guanidinomethyl]phenylalanine N-methylamide(751476-44-5)
• EPA Substance Registry System: N-[4-hydroxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-[N,N'-bis(benzyloxycarbonyl)guanidinomethyl]phenylalanine N-methylamide(751476-44-5)

Safety Data

• Hazardous Substances Data: 751476-44-5(Hazardous Substances Data)

Upstream product

• 484685-81-6 N-[4-tert-butyloxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-cyanophenylalanine N-methylamide 
• 484685-84-9 N-[4-hydroxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-cyanophenylalanine N-methylamide 
• 228260-15-9 tert-butyl (S)-(3-(4-cyanophenyl)-1-(methylamino)-1-oxopropan-2-yl)carbamate 
• 152120-55-3 N,N-bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine 

Downstream Products

• 484685-96-3 N-[4-(N-benzyloxyamino)-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-[N,N'-bis(benzyloxycarbonyl)guanidinomethyl]phenylalanine N-methylamide 

Relevant articles and documents

Highly water-soluble matrix metalloproteinases inhibitors and their effects in a rat adjuvant-induced arthritis model.

A new series of succinate-based dual inhibitors against matrix metalloproteinases (MMPs) and tumor necrosis factor alpha converting enzyme (TACE) possessing highly-water solubility was designed, synthesized, and evaluated for enzyme inhibition. Incorporat