484689-23-8Relevant academic research and scientific papers
Synthesis and properties of nonpolar DNA (arylalkyl)phosphonates
Amberg, Stefan,Engels, Joachim W.
, p. 2503 - 2517 (2007/10/03)
The eight (arylalkyl)-modified phosphoramidites (=(arylalkyl)phosphonamidites) 1-8 (Fig. 2) were synthesized (Schemes 1-3) and incorporated at different positions into 2′-deoxyoligonucleotides. The [P(R)]-and [P(S)]-diastereoisomers of the hexanucleotides
Phenylalkyl backbone modified oligodeoxynucleotides, their synthesis and the influence of the alkyl chain length
Amberg,Engels
, p. 1275 - 1278 (2007/10/03)
Phenylalkyl modified phosphoramidites (alkyl chain length n = 1, 2, 3, 5; Fig. 1) were synthesised and incorporated into a DNA hexamer (5′-d(GCCp-GCG); p = place of modification). The obtained diastereomeres were separated by RP-HPLC. After hybridisation
