486-90-8

Basic information

• Product Name: thermospine
• Synonyms: thermospine;7,14-Methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one,1,3,4,6,7,13,14,14a-octahydro-, (7R,14R,14aS)-;(7R)-7,7aβ,8,9,10,11,13,14-Octahydro-7β,14β-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one;7,14-Methano-4H,6H-dipyrido[1,2-A:1',2'-E][1,5]diazocin-4-one, 7,7A,8,9,10,11,13,14-octahydro-, [7R-(7.alpha.,7A.alpha.,14.alpha.)]-;Nsc21725;Thermopsine,1-;(7R,14R,14aS)-1,3,4,6,7,13,14,14a-Octahydro-7,14-methano-2H,11H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-11-one;l-Thermopsine
• CAS NO: 486-90-8
• Molecular Formula: C15H20N2O
• Molecular Weight: 244.33
• Mol File: 486-90-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 205-206℃
• Boiling Point: 455.6°Cat760mmHg
• Flash Point: 216.3°C
• Appearance: /
• Density: 1.22
• Vapor Pressure: 1.73E-08mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: thermospine(CAS DataBase Reference)
• NIST Chemistry Reference: thermospine(486-90-8)
• EPA Substance Registry System: thermospine(486-90-8)

Safety Data

• Hazardous Substances Data: 486-90-8(Hazardous Substances Data)

Usage

General Description

Thermospine is a chemical that has been developed for use in thermal energy storage applications. It is a phase change material that undergoes a solid-liquid transition at specific temperatures, allowing it to store and release large amounts of heat. Thermospine has been designed to have a high heat capacity and excellent thermal stability, making it an efficient and reliable option for thermal energy storage systems. Its ability to store and release heat at precise temperatures makes it a valuable component in a variety of applications, including solar energy systems, building insulation, and industrial heat storage. Overall, thermospine offers a promising solution for the efficient and sustainable storage of thermal energy.

InChI:InChI=1/C15H20N2O/c18-15-6-3-5-14-11-8-12(10-17(14)15)13-4-1-2-7-16(13)9-11/h3,5-6,11-13H,1-2,4,7-10H2/t11-,12+,13-/m0/s1

Upstream product

• 109600-96-6 (+/-)-(7at)-7,7a,8,9,10,11,13,14-octahydro-6H-7r,14c-methano-dipyrido[1,2-a;1',2'-e][1,5]diazocinylium; bromide 
• 53439-74-0 ethyl(+/-)-(1RS,9aSR)-1,2,3,6,7,8,9,9a-octahydro-4-oxo-9aH-quinolizine-1-carboxylate 
• 122059-35-2 ethyl (1-benzylpiperidin-2-yl)acetate 
• 183859-36-1 methyl (+/-)-N-(tert-butyloxycarbonyl)piperidin-2-ylacetate 
• 34389-12-3 (+/-)-(3c-[2]pyridyl-(9ar)-octahydro-quinolizin-1c-yl)-methanol 
• 75928-96-0 (+/-)-(1S,10R)-1-(hydroxymethyl)octahydroquinolizin-4-one 
• 890936-85-3 (+/-)-ethyl 3-ethoxy-2-[1-benzylpiperidin-2-yl]propionate 
• 890936-76-2 ethyl 2-[N-benzylpiperidin-2-yl]acrylate 
• 142-08-5 2-Pyridone 

Downstream Products

• 486-89-5 (+/-)-thermopsine 

Relevant articles and documents

The Enantioselective Total Synthesis of Bisquinolizidine Alkaloids: A Modular “Inside-Out” Approach

Bisquinolizidine alkaloids are characterized by a chiral bispidine core (3,7-diazabicyclo[3.3.1]nonane) to which combinations of an α,N-fused 2-pyridone, an endo- or exo-α,N-annulated piperidin(on)e, and an exo-allyl substituent are attached. We developed a modular “inside-out” approach that permits access to most members of this class. Its applicability was proven in the asymmetric synthesis of 21 natural bisquinolizidine alkaloids, among them more than ten first enantioselective total syntheses. Key steps are the first successful preparation of both enantiomers of C2-symmetric 2,6-dioxobispidine by desymmetrization of a 2,4,6,8-tetraoxo precursor, the construction of the α,N-fused 2-pyridone by using an enamine-bromoacrylic acid strategy, and the installation of endo- or, optionally, exo-annulated piperidin(on)es.