486395-00-0

Upstream product

• 486394-99-4 tert-Butyl-[(2R,4S,5R)-4-(2-[1,3]dithian-2-yl-ethyl)-2-phenyl-[1,3]dioxan-5-yloxy]-dimethyl-silane 
• 221455-79-4 tert-Butyl-[(2R,4S,5R)-4-(2-iodo-ethyl)-2-phenyl-[1,3]dioxan-5-yloxy]-dimethyl-silane 
• 221455-78-3 2-[(2R,4S,5R)-5-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-[1,3]dioxan-4-yl]-ethanol 
• 623-47-2 propynoic acid ethyl ester 
• 486394-72-3 (2R,4S,5R)-4-(2-[1,3]Dithian-2-yl-ethyl)-2-phenyl-[1,3]dioxan-5-ol 

Downstream Products

• 486394-81-4 (E)-4-((4aR,5aS,6aR,8S,9R,10aS,11aR,13aS)-2,2,9,10a-Tetramethyl-9-trimethylsilanyloxy-dodecahydro-1,3,5,7,11-pentaoxa-benzo[4,5]cyclohepta[1,2-b]naphthalen-8-yl)-but-2-enoic acid benzyl ester 
• 486394-97-2 (E)-4-((4aR,5aS,6aR,8S,9R,10aS,11aR,13aS)-9-Hydroxy-2,2,9,10a-tetramethyl-dodecahydro-1,3,5,7,11-pentaoxa-benzo[4,5]cyclohepta[1,2-b]naphthalen-8-yl)-but-2-enoic acid benzyl ester 
• 486394-75-6 (E)-4-[(2R,4aR,6S,7R,9aS)-7-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-1,3,5-trioxa-benzocyclohepten-6-yl]-2-methyl-but-2-enoic acid ethyl ester 
• 486394-76-7 {(2R,3R)-3-[(2R,4aR,6S,7R,9aS)-7-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-1,3,5-trioxa-benzocyclohepten-6-ylmethyl]-2-methyl-oxiranyl}-methanol 
• 486395-02-2 (E)-4-[(2R,4aR,6S,7R,9aS)-7-(tert-Butyl-dimethyl-silanyloxy)-2-phenyl-hexahydro-1,3,5-trioxa-benzocyclohepten-6-yl]-2-methyl-but-2-en-1-ol 
• 486394-77-8 tert-Butyl-dimethyl-[(2R,4aR,6S,7R,9aS)-6-((2R,3R)-3-methyl-3-vinyl-oxiranylmethyl)-2-phenyl-hexahydro-1,3,5-trioxa-benzocyclohepten-7-yloxy]-silane 
• 486394-74-5 (E)-4-((2R,4aR,6S,7R,9aS)-7-Hydroxy-2-phenyl-hexahydro-1,3,5-trioxa-benzocyclohepten-6-yl)-2-methyl-but-2-enoic acid ethyl ester 
• 486394-70-1 (2R,4aR,5aS,7R,8S,9aR,11aS)-8-Methyl-2-phenyl-8-vinyl-decahydro-1,3,5,9-tetraoxa-dibenzo[a,d]cyclohepten-7-ol 
• 486394-73-4 (3aS,4aR,7R,8aS,10aR)-7-Phenyl-octahydro-1,4,6,8-tetraoxa-benzo[f]azulen-2-one 
• 378742-07-5 C₆₁H₈₂O₁₃ 
• 378741-91-4 C₃₄H₄₃O₁₀P 
• 486394-71-2 (E)-3-[(2R,4S,5R)-4-(3-Oxo-propyl)-2-phenyl-[1,3]dioxan-5-yloxy]-acrylic acid ethyl ester 

Relevant academic research and scientific papers

Total synthesis of (-)-gambierol

The first total synthesis of (-)-gambierol (1), a marine polycyclic ether toxin, has been achieved. Key features of the successful synthesis include (1) a convergent union of the ABC and EFGH ring fragments (5 and 6, respectively) via our developed B-alky