486445-46-9Relevant academic research and scientific papers
PIPERIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN
-
Paragraph 0169, (2017/01/02)
The present invention relates to compounds having dual pharmacological activity towards both the sigma (σ) receptor, and the μ-opiod receptor and more particularly to piperidene compounds having this pharmacological activity, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
PIPERIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN
-
Page/Page column 134, (2015/07/07)
The present invention relates to compounds having dual pharmacological activity towards both the sigma receptor and the mu-opioid receptor, and more particularly to piperidine compounds having this pharmacological activity, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.
SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS
-
Page column 114, (2010/02/06)
This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therepeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier.
