487003-24-7Relevant academic research and scientific papers
Synthesis of (±)-strychnofoline via a highly convergent selective annulation reaction
Lerchner, Andreas,Carreira, Erick M.
, p. 8208 - 8219 (2007/10/03)
Studies aimed at preparing (±)-strychnofoline by total synthesis are detailed. The route described makes use of a recently developed MgI 2-mediated ring-expansion reaction of spiro[cyclopropan-1,3′- oxindole] with a cyclic disubstituted aldimin
First total synthesis of (±)-strychnofoline via a highly selective ring-expansion reaction
Lerchner, Andreas,Carreira, Erick M.
, p. 14826 - 14827 (2007/10/03)
An efficient synthesis of the antitumor alkaloid (±)-strychnofoline is documented. Key to the development of the highly convergent strategy delineated is the coupling of a cyclic imine with spiro[cyclopropan-1,3'-oxindole], which takes place in a highly d
