487047-97-2

Basic information

• Product Name: (2R,3R)-methyl 2-fluoro-3-hydroxy-2-methyl-3-phenylpropanoate
• Synonyms: (2R,3R)-methyl 2-fluoro-3-hydroxy-2-methyl-3-phenylpropanoate
• CAS NO: 487047-97-2
• Molecular Weight: 212.221
• Mol File: 487047-97-2.mol

Chemical Properties

• CAS DataBase Reference: (2R,3R)-methyl 2-fluoro-3-hydroxy-2-methyl-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-methyl 2-fluoro-3-hydroxy-2-methyl-3-phenylpropanoate(487047-97-2)
• EPA Substance Registry System: (2R,3R)-methyl 2-fluoro-3-hydroxy-2-methyl-3-phenylpropanoate(487047-97-2)

Safety Data

• Hazardous Substances Data: 487047-97-2(Hazardous Substances Data)

Upstream product

• 104015-38-5 tert-butyl 2-benzoylpropionate 
• 144462-33-9 (R)-methyl 2-fluoro-2-methyl-3-oxo-3-phenyl-propionate 
• 487047-93-8 (R)-tert-butyl 2-fluoro-2-methyl-3-oxo-3-phenyl-propionate 

Downstream Products

• 487048-00-0 (2R,3S)-3-Azido-2-fluoro-2-methyl-3-phenyl-propionic acid methyl ester 

Relevant articles and documents

Highly enantioselective fluorination reactions of β-ketoesters and β-ketophosphonates catalyzed by chiral palladium complexes

Using chiral palladium enolates as key intermediates, efficient catalytic enantioselective fluorination reactions of active methine compounds have been developed. These reactions can be conducted in alcoholic solvents without any precaution to exclude wat

An efficient enantioselective fluorination of various β-ketoesters catalyzed by chiral palladium complexes

Reflecting the importance of fluorinated organic compounds in medicinal chemistry, development of an efficient method for catalytic enantioselective fluorination is increasingly desirable. Using a novel palladium complex 2 (1-2.5 mol %), various β-ketoest