488-64-2

Usage

Uses

Used in Pharmaceutical Formulations:
Inosose is used as a drug carrier or stabilizer for enhancing the efficacy and stability of pharmaceutical formulations.
Used in Production of Natural Products and Biofuels:
Inosose serves as a key component in the production of natural products and biofuels, contributing to the development of sustainable energy sources and eco-friendly products.
Used in Therapeutic Applications:
Inosose is used as a potential therapeutic agent for the treatment of various diseases, including cancer and neurodegenerative disorders, due to its promising medicinal properties.
Used in Research and Development:
Inosose is utilized in research and development for further exploration of its potential applications and to unlock new possibilities in the fields of medicine, biotechnology, and energy.

InChI:InChI=1/C6H10O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-5,7-11H/t1?,2-,3+,4+,5-

Upstream product

• 87-89-8 D-myo-inositol 
• 319-89-1 tetrahydroxy-1,4-quinone 
• 576-63-6 cis-inositol 
• 106600-11-7 2,3,4,5,6-penta-O-benzyl-scyllo-inosose 

Downstream Products

• 24924-09-2 1,2,3,5-tetraacetoxy-benzene 
• 642-96-6 1,2,3,4-tetrahydroxybenzene 
• 87-89-8 D-myo-inositol 
• 527-42-4 1-deoxy-scyllo-inositol 
• 7045-48-9 myo-inosose-⁽²⁾-phenylhydrazone 
• 21450-56-6 1,2,3,4-tetramethoxybenzene 
• 35896-58-3 2,3,4,5-tetramethoxytoluene 
• 95778-33-9 1,2,3,4-tetramethoxy-5-methyl-6-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)benzene 
• 69422-80-6 ubiquinol-3 
• 1254-38-2 inositol peracetate 
• 20108-71-8 hexa-O-acetyl-epi-inositol 
• 488-58-4 epi-Inositol 
• 15110-70-0 Croconic acid dianion 
• 28737-41-9 Rhodizonate dianion 

Relevant academic research and scientific papers

Protecting group directed stereoselective reduction of an epi-inosose: Efficient synthesis of epi-inositol

A facile and high yielding synthesis of epi-inositol via stereoselective reduction of a pentaprotected epi-inosose is reported. Extent of stereoselectivity during the hydride reduction appears to depend on the ability of the substrate to complex with metal ions in the reducing agent.

Kinetics of the reaction catalyzed by inositol dehydrogenase from Bacillus subtilis and inhibition by fluorinated substrate analogs

Inositol dehydrogenase (EC 1.1.1.18) from Bacillus subtilis catalyzes the oxidation of myo-inositol to scyllo-inosose by transfer of the equatorial hydride of the substrate to NAD+. This is a key enzyme in the metabolism of myo-inositol, a primary carbon source for soil bacteria. In light of our recent discovery that the enzyme has a broad substrate spectrum while maintaining high stereoselectivity, we seek a more thorough understanding of the enzyme and its active site. We have examined the kinetics of the recombinant enzyme, and synthesized fluorinated substrate analogues as competitive inhibitors. We have evaluated all rate constants in the ordered, sequential Bi Bi mechanism. No steady-state kinetic isotope effect is observed using myo-[2-2H]-inositol, indicating that the chemical step of the reaction is not rate-limiting. We have synthesized the substrate analogs 2-deoxy-2-fluoro-myo-inositol, its equatorial analog 1-deoxy-1-fluoro-scyllo- inositol, the gem-difluorinated analog 1-deoxy-1,1-difluoro-scyllo-inositol, and the sugar analog α-D-glucosyl fluoride. Of these, 1-deoxy-1-fluoro- scyllo-inositol showed no inhibition, while all others tested had Ki values comparable to the Km values of the analogous substrates myo-inositol and α-D-glucose.

Stereochemical recognition of doubly functional aminotransferase in 2-deoxystreptamine biosynthesis

The doubly functional aminotransferase BtrS in the 2-deoxystreptamine (DOS) biosynthesis, in which two transaminations are involved, was characterized by a genetic as well as a chemical approach with the heterologously expressed enzyme. The gene disruptio

Stereoselective oxidation of protected inositol derivatives catalyzed by inositol dehydrogenase from Bacillus subtilis

Inositol dehydrogenase (EC 1.1.1.18) from Bacillus subtilis is shown to have a nonpolar cavity adjacent to the active site, allowing racemic protected inositol derivatives such as 4-O-benzyl-myo-inositol to be recognized with very high apparent stereoselectivity.

The oxidation of partially acylated myoinositols

1,3,4,6-Tetrakis-and 1,3,4,5,6-pentakis-acylmyoinositols are obtained by the controlled catalyzed acylation of myoinositol. The extent of the substitution depends both on the reaction conditions and the structure of the acylating agent, including steric f

The Selectivity of Attack by the Hydroxyl Radical on Myoinositol, and the Importance of Stereoelectronic Factors upon Radical Rearrangement: an Electron Spin Resonance Conformational-analysis Study

E.s.r. spectroscopy has been employed to show that the reaction of .OH with the model substrate myoinositol is unselective; at pH 4, e.s.r. signals of all possible radicals produced by C-H abstraction are detected.A conformational analysis based on the hy