488118-61-2Relevant academic research and scientific papers
(1-Benzimidazolonyl)alanine (Bia): Preliminary investigations into a potential tryptophan mimetic
Huber, Vincent J,Arroll, Thomas W,Lum, Christopher,Goodman, Burton A,Nakanishi, Hiroshi
, p. 6729 - 6733 (2002)
The new amino acid (1-benzimidazolonyl)alanine (Bia) was synthesized as a potential biomimetic replacement of tryptophan. The replacement of tryptophan with this amino acid in a truncated analog of p53 showed nearly identical binding to HDM2 as the same l
