488721-35-3

Upstream product

• 488721-31-9 (1R,6S)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-methyl-7-triisopropylsilanyloxy-hept-2-yn-1-ol 
• 637012-19-2 (4R,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-((E)-propenyl)-tetrahydro-pyran-2-one 
• 488721-45-5 (E)-(3R,5S)-3,5-Bis-triethylsilanyloxy-oct-6-enoic acid butyl ester 
• 488721-32-0 Benzoic acid (E)-(1R,6S)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-7-triisopropylsilanyloxy-hept-2-enyl ester 
• 488721-26-2 (E)-(3R,5S)-3,5-Bis-triethylsilanyloxy-oct-6-enal 
• 488721-33-1 Benzoic acid (E)-(1R,6S)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-7-hydroxy-6-methyl-hept-2-enyl ester 
• 488721-29-5 [(2R,4S,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-((E)-propenyl)-tetrahydro-pyran-2-yl]-acetic acid ethyl ester 
• 488721-28-4 [(2R,4S,6S)-4-Hydroxy-6-((E)-propenyl)-tetrahydro-pyran-2-yl]-acetic acid ethyl ester 
• 488721-25-1 (E)-(S)-5-Hydroxy-3-oxo-oct-6-enoic acid butyl ester 
• 488721-27-3 (2E,8E)-(5S,7S)-5,7-Dihydroxy-deca-2,8-dienoic acid ethyl ester 
• 488721-24-0 6-((E)-(S)-2-Hydroxy-pent-3-enyl)-2,2-dimethyl-[1,3]dioxin-4-one 
• 98-88-4 benzoyl chloride 
• 488721-34-2 Benzoic acid (E)-(1R,6S)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-7-oxo-hept-2-enyl ester 
• 488721-30-8 [(2R,4R,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-(2-oxo-propyl)-tetrahydro-pyran-2-yl]-acetic acid ethyl ester 

Downstream Products

• 488721-38-6 [4-(tert-butyl-dimethyl-silanyloxy)-6-(3-{6-[2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-1-(2,4,6-triisopropyl-phenylselanyl)-ethyl]-3-methyl-tetrahydro-pyran-2-yl}-2-hydroxy-propyl)-tetrahydro-pyran-2-yl]-acetic acid methyl ester 
• 488721-36-4 Benzoic acid (E)-(1R,6S,7R,9R)-10-[(2R,4R,6R)-4-(tert-butyl-dimethyl-silanyloxy)-6-ethoxycarbonylmethyl-tetrahydro-pyran-2-yl]-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-7,9-dihydroxy-6-methyl-dec-2-enyl ester 

Relevant academic research and scientific papers

Total synthesis of leucascandrolide A

A compound that could never be isolated again despite intensive efforts after it was first found in the sponge Leucascandra caveolata in 1996 is leucascandrolide A (1). An enantioselective, convergent total synthesis of this polyoxygenated marine macrolid

Leucascandrolide A: Synthesis and Related Studies

The total synthesis of the biologically active marine natural product leucascandrolide A is reported. A convergent strategy is employed, allowing for the rapid assembly of the macrolide moiety. Key steps of our approach include the diastereoselective addi