488791-45-3

Upstream product

• 187527-25-9 (-)-(5S)-5,7-bis{[tert-butyl(dimethyl)silyl]oxy}-4,4-dimethylheptan-3-one 
• 488791-43-1 (6Z,10E)-(2S,8S,9S)-9-(tert-Butoxy-diphenyl-silanyloxy)-2,6,8,10-tetramethyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dienal 
• 488791-41-9 (6Z,10E)-(2S,8S,9S)-9-(tert-Butoxy-diphenyl-silanyloxy)-2,6,8,10-tetramethyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dien-1-ol 
• 355009-17-5 3,5-bis-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-pentanoic acid phenyl ester 
• 355009-03-9 5-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,2-dimethyl-pentanoic acid phenyl ester 
• 89922-82-7 3-(tert-butyldimethylsilanyloxy)propionaldehyde 

Downstream Products

• 488791-49-7 (12Z,16E)-(3S,6R,7S,8S,14S,15S)-15-(tert-Butoxy-diphenyl-silanyloxy)-3,7-bis-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4,4,6,8,12,14,16-heptamethyl-17-(2-methyl-thiazol-4-yl)-heptadeca-12,16-dien-5-one 
• 488791-47-5 (12Z,16E)-(3S,6R,7S,8S,14S,15S)-15-(tert-Butoxy-diphenyl-silanyloxy)-1,3,7-tris-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,12,14,16-heptamethyl-17-(2-methyl-thiazol-4-yl)-heptadeca-12,16-dien-5-one 

Relevant academic research and scientific papers

Conformation-activity relationships in polyketide natural products. Towards the biologically active conformation of epothilone

The conformation-activity relationships for the biologically active polyketide, epothilone, have been determined. Computer-based molecular modeling and high field NMR techniques have provided the solution preferences for epothilones 1 and 2. For the C1-C8