488829-83-0

Basic information

• Product Name: 9-Phenanthrenamine, N-(phenylmethylene)-
• CAS NO: 488829-83-0
• Molecular Formula: C21H15N
• Molecular Weight: 281.357
• Mol File: 488829-83-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-Phenanthrenamine, N-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: 9-Phenanthrenamine, N-(phenylmethylene)-(488829-83-0)
• EPA Substance Registry System: 9-Phenanthrenamine, N-(phenylmethylene)-(488829-83-0)

Safety Data

• Hazardous Substances Data: 488829-83-0(Hazardous Substances Data)

Upstream product

• 947-73-9 9-Aminophenanthrene 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Stereocontrolled synthesis of anticancer β-lactams via the Staudinger reaction

Stereocontrolled synthesis of novel β-lactams using polyaromatic imines following the Staudinger reaction has been accomplished. The effects of domestic microwave irradiation on this type of reaction have been investigated. Formation of trans-β-lactams has been explained through isomerization of the enolates formed during the reaction of acid chloride (equivalent) with imines in the presence of triethylamine. A donor-acceptor complex pathway is believed to be involved in the formation of cis-β-lactams. The effect of a peri hydrogen has been found to be significant in controlling the stereochemistry of the resulting β-lactams. SAR has identified β-lactams with anticancer activity. The presence of an acetoxy group has proven obligatory for their anticancer activity.