4889-70-7

Usage

Explanation

This is the chemical name of the compound, which is also known as Diclofenac.

Explanation

Diclofenac belongs to a class of drugs called NSAIDs, which are commonly used to reduce inflammation and pain.

Explanation

Diclofenac works by blocking the production of certain chemicals in the body that cause pain and inflammation, such as prostaglandins.

Explanation

Diclofenac is often prescribed to treat various conditions that involve pain and inflammation, including arthritis, muscle pain, and menstrual cramps.

Explanation

This medication can be found in different forms, making it suitable for various routes of administration, such as oral or topical application.

Explanation

Diclofenac can be taken orally or applied directly to the affected area, depending on the form of the medication and the specific condition being treated.

Explanation

While effective in relieving pain and inflammation, Diclofenac can have serious side effects, especially when taken in high doses or for an extended period of time. It is important to use this medication as directed by a healthcare professional.

Classification

Nonsteroidal anti-inflammatory drug (NSAID)

Function

Inhibits production of pain-causing chemicals

Common uses

Arthritis, muscle pain, menstrual cramps

Available forms

Tablets, capsules, topical gels

Administration

Oral or topical

Caution

Serious side effects with high doses or extended use

InChI:InChI=1/C14H11ClO2/c15-12-7-5-10(6-8-12)9-11-3-1-2-4-13(11)14(16)17/h1-8H,9H2,(H,16,17)

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 108-90-7 chlorobenzene 
• 85-56-3 2-(4-chlorobenzoyl)benzoic acid 
• 6630-33-7 ortho-bromobenzaldehyde 
• 106-39-8 bromochlorobenzene 
• 60081-00-7 (2-bromophenyl)(4-chlorophenyl)methanol 
• 124-38-9 carbon dioxide 
• 92188-91-5 1-bromo-2-(4-chlorobenzyl)benzene 

Downstream Products

• 4889-69-4 3-(4-chlorophenyl)phthalide 
• 1456693-97-2 3-(4-chlorophenyl)-3-hydroxy-2-methoxyisoindolin-1-one 
• 15067-89-7 2-Chlormethyl-4'-chlor-diphenylmethan 
• 10324-04-6 2-(4-chlorobenzyl)phenylacetic acid 
• 10305-56-3 <α-(p-Chlorphenyl)-o-tolyl>-acetonitril 
• 10324-38-6 α-Brom-o-(p-chlorbenzyl)-toluol 
• 569657-07-4 2-(4-chlorobenzyl)-N-methoxybenzamide 
• 632340-65-9 2-[4'-chloro(bromobenzyl)]benzoic acid 
• 4887-99-4 2-chloroanthrone 
• 15139-43-2 Di-<2-(4-chlor-benzyl)-benzyl>-ether 
• 10324-39-7 2-Hydroxymethyl-4'-chlor-diphenylmethan 
• 10324-40-0 methyl 2-(4-chlorobenzyl)benzoate 

Relevant academic research and scientific papers

Copper-catalyzed aerobic double functionalization of benzylic C(sp3)-H bonds for the synthesis of 3-hydroxyisoindolinones

A copper-catalyzed aerobic 3-hydroxyisoindolinone synthesis was developed via the benzylic double C(sp3)-H functionalization of 2-alkylbenzamides. In this reaction, molecular oxygen was used as both an oxidant for C(sp3)-H functionalization and an oxygen source. Our method can be extended to diverse benzylic C(sp3)-H bonds and shows excellent functional group tolerance. This journal is

A Novel Three-Step Tandem Reaction for Efficient Syntheses of Bulky Anthracenyl Esters from 2-Benzylbenzoic Acids

Bulky anthracenyl esters could be efficiently synthesized from 2-benzylbenzoic acids via a novel three-step tandem reaction containing intramolecular Friedel-Crafts acylation, enolization, and esterification. A mechanism for the tandem reaction is proposed.

Efficient synthesis of isobenzofuran-1(3H)-ones (Phthalides) and selected biological evaluations

The studies presented here deal with the convenient and efficient one-step conversion of o-alkylbenzoic acids into their corresponding isobenzofuran-1 (3H)-ones (phthalides) using NaBrO3/NaHSO3 in a two-phase system. A range of o-alkylbenzoic acids was used with the object of getting a variety of phthalide derivatives as multipurpose biologically active compounds. Seventeen phthalides have been synthesized and tested for cytotoxicity, antibacterial and antifungal activities. Some of these compounds showed promising cytotoxic effects against Artemia salina. Compounds 4j-4p were highly active against Gram-negative and Gram-positive bacteria among all tested compounds. In the fungicidal assay, the compounds showed a broad spectrum of activity against six fungi. All compounds were characterized via elemental analysis, UV, IR, mass and-NMR spectroscopy. ECV · Editio Cantor Verlag.

An alternative method for the synthesis of γ-lactones by using cesium fluoride-celite/acetonitrile combination

A variety of 2-(1-bromoalkyl) benzoic acids 4 undergo intramolecular nucleophilic substitution reaction when treated with a CsF-Celite as solid base in acetonitrile under reflux condition to give the corresponding cyclized phthalides in moderate to very good yield. These 2-(1-bromoalkyl) benzoic acids 4 are formed by the α-bromination of 2-alkylbenzoic acids 3 using N-bromosuccinimide and a catalytic amount of α,α′ -azoisobutyronitrile in carbon tetrachloride under reflux.

Synthesis of spirodienones by intramolecular ipso-cyclization of N-methoxy-(4-halogenophenyl)amides using [hydroxy(tosyloxy)iodo]benzene in trifluoroethanol

Spirodienones bearing the 1-azaspiro[4.5]decane ring system have been synthesized from N-methoxy-(4-halogenophenyl)amides by the intramolecular ipso attack of a nitrenium ion generated with [hydroxy(tosyloxy)iodo]-benzene in trifluoroethanol.