489453-06-7

Upstream product

• 762233-34-1 1-benzyl 2-methyl (2S,4R)-4-aminopyrrolidine-1,2-dicarboxylate 
• 189215-90-5 1-benzyl 2-methyl (2S,4R)-4-(tert-butoxycarbonylamino)pyrrolidine-1,2-dicarboxylate 
• 393524-17-9 (2S,4R)-4-tert-Butoxycarbonylamino-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 
• 1212395-57-7 methyl (2S,4R)-4-amino-1-[benzyloxycarbonyl]pyrrolidine-2-carboxylate hydrochloride 

Downstream Products

• 489453-08-9 C₄₇H₅₆N₈O₁₁ 
• 489447-25-8 C₄₃H₅₁N₉O₁₀ 
• 803706-19-6 (2S,4R)-4-({(2S,4R)-1-Benzyloxycarbonyl-4-[((2S,4R)-1-benzyloxycarbonyl-4-tert-butoxycarbonylamino-pyrrolidine-2-carbonyl)-amino]-pyrrolidine-2-carbonyl}-amino)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 
• 489453-07-8 (2S,4R)-4-({(2S,4R)-1-Benzyloxycarbonyl-4-[((2S,4R)-1-benzyloxycarbonyl-4-tert-butoxycarbonylamino-pyrrolidine-2-carbonyl)-amino]-pyrrolidine-2-carbonyl}-amino)-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 

Relevant academic research and scientific papers

Trends in asymmetric Michael reactions catalysed by tripeptides in combination with an achiral additive in different solvents

The potential of tripeptides 3, 6 and 12 as chiral catalysts for asymmetric Michael addition reactions in the presence of an achiral additive has been tested in different solvents (CHCI3, acetone, DMF, DMSO and the room-temperature ionic liquid

Synthesis and DNA binding properties of saturated distamycin analogues

A series of saturated heterocyclic analogues of distamycin were prepared and examined. A fluorescent intercalator displacement (FID) assay conducted on p[dA]-p[dT] DNA to obtain C50 values and a hairpin deoxyoligonucleotide containing an A/T-rich binding site was used to evaluate DNA binding affinity. It is observed that saturated heterocycles greatly reduce the DNA binding relative to distamycin.