490-55-1 Usage
Originator
Aamphisol,RJR
Manufacturing Process
Thiourea reacted with α-bromophenylacetonitrile and as a result of this
reaction 2-(cyanophenylmethyl)isothiourea was obtained.
By cyclisation of the 2-(cyanophenylmethyl)isothiourea 2,4-diamino-5-
phenylthiazole (amiphenazol) was produced.
Therapeutic Function
Respiratory stimulant, Barbiturate antagonist,
Morphine antagonist
Purification Methods
The thiazole crystallises from aqueous EtOH or water. Store it in the dark under N2. The hydrochloride has m 273-274o(dec) (from MeOH/EtOAc), and the picrate has m 189-191o(dec) (from H2O). [Davies et al. J Chem Soc 3491 1950, Dodson & Turner J Am Chem Soc 73 4517 1951, Beilstein 27 III/IV 5139.]
Check Digit Verification of cas no
The CAS Registry Mumber 490-55-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 490-55:
(5*4)+(4*9)+(3*0)+(2*5)+(1*5)=71
71 % 10 = 1
So 490-55-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3S/c10-8-7(13-9(11)12-8)6-4-2-1-3-5-6/h1-5H,10H2,(H2,11,12)
490-55-1Relevant articles and documents
Composition of matter having bioactive properties
-
, (2008/06/13)
Particles of coordinated complex comprising a basic, hydrous polymer and a capacitance adding compound, as well as methods for their production, are described. These complexes exhibit a high degree of bioactivity making them suitable for a broad range of applications through their incorporation into conventional vehicles benefiting from antimicrobial and similar properties.
