490039-83-3

Basic information

• Product Name: Benzonitrile, 2-iodo-4-methoxy-
• CAS NO: 490039-83-3
• Molecular Formula: C8H6INO
• Molecular Weight: 259.046
• Mol File: 490039-83-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 2-iodo-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 2-iodo-4-methoxy-(490039-83-3)
• EPA Substance Registry System: Benzonitrile, 2-iodo-4-methoxy-(490039-83-3)

Safety Data

• Hazardous Substances Data: 490039-83-3(Hazardous Substances Data)

Upstream product

• 874-90-8 4-methoxybenzonitrile 
• 96-96-8 4-methoxy-2-nitroaniline 
• 38469-83-9 4-methoxy-2-nitro-benzonitrile 
• 38487-85-3 4-methoxyanthranilonitrile 

Downstream Products

• 1619256-47-1 4-methoxy-2-(2-methylallyl)benzonitrile 
• 1431758-12-1 C₁₁H₁₁NO₂ 
• 1431758-11-0 C₁₂H₁₃NO₂ 
• 1431758-09-6 C₁₇H₁₅NO₃ 
• 1431758-08-5 C₁₆H₁₃NO₂ 
• 1369864-41-4 2-iodo-4-methoxybenzamide 
• 33902-32-8 6-methoxy-3-(4-methoxyphenyl)-1H-2-benzopyran-1-one 
• 65908-33-0 6-methoxy-2,3-diphenyl-1H-inden-1-one 
• 874-90-8 4-methoxybenzonitrile 

Relevant articles and documents

Palladium-catalyzed highly selective ortho-halogenation (I, Br, Cl) of arylnitriles via sp2 C-H bond activation using cyano as directing group

A palladium-catalyzed ortho-halogenation (I, Br, Cl) of arylnitrile is described. The optimal reaction conditions were identified after examining various factors such as catalyst, additive, solvent, and reaction temperature. Using cyano as the directing group, the halogenation reaction gave good to excellent yields. The method is compatible to the arylnitriles with either electron-withdrawing or electron-donating groups. The reaction is available to the substrate in at least gram scale. The present method was successfully applied to the synthesis of the precursors of paucifloral F and isopaucifloral F.

Therapeutic Compounds and Their Use in Treating Diseases and Disorders

The invention provides novel therapeutic compounds, pharmaceutical compositions comprising these compounds, and methods for using these compounds and compositions to treat diseases and disorders, such as cancer.