491612-10-3

Upstream product

• 1246639-99-5 C₁₀H₁₁N₃O₂ 
• 85907-78-4 ethyl 2-(3,4-diaminophenyl)acetate 
• 1246639-99-5 C₁₀H₁₁N₃O₂ 

Downstream Products

• 1246639-71-3 4-chlorobenzyl 4-(2-1H-benzotriazol-5-ylacetyl)piperazine-1-carboxylate 
• 106429-67-8 (1H-benzo[d][1,2,3]triazol-5-yl)methanol 
• 70938-42-0 1H-1,2,3-benzotriazole-5-carbaldehyde 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS AS AUTOTAXIN INHIBITORS

Compounds of the formula (I), in which Het, R, X, Y, R1 and p have the meanings indicated in claim 1, are autotaxin inhibitors and can be employed for the treatment of tumours.

PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS

The present invention relates to piperidine and pyrazine derivatives according to formulae (Ia), (Ib) and (II) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers.