70938-42-0

Usage

Uses

Used in Pharmaceutical Industry:
1H-Benzo[d][1,2,3]triazole-5-carbaldehyde is used as a building block for the synthesis of various pharmaceuticals. Its unique structure and versatile reactivity make it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
1H-Benzo[d][1,2,3]triazole-5-carbaldehyde is used as a building block for the synthesis of agrochemicals. Its properties allow for the creation of effective compounds for use in agriculture.
Used in Advanced Materials:
1H-Benzo[d][1,2,3]triazole-5-carbaldehyde is used as a building block in the development of advanced materials. Its unique structure contributes to the creation of innovative materials with specialized properties.
Used in Fluorescent Compounds:
1H-Benzo[d][1,2,3]triazole-5-carbaldehyde is used as a precursor in the preparation of fluorescent compounds. Its structure allows for the development of compounds with specific light-emitting properties.
Used in Metal-Organic Frameworks:
1H-Benzo[d][1,2,3]triazole-5-carbaldehyde is used as a precursor in the synthesis of metal-organic frameworks. Its versatile reactivity contributes to the formation of complex structures with potential applications in various fields.

Upstream product

• 113053-50-2 1H-Benzotriazole-5-carboxylic acid methyl ester 
• 68-12-2 N,N-dimethyl-formamide 
• 1246639-99-5 C₁₀H₁₁N₃O₂ 
• 491612-10-3 C₈H₇N₃O₂ 
• 23814-12-2 1h-benzotriazole-5-carboxylic acid 
• 106429-67-8 (1H-benzo[d][1,2,3]triazol-5-yl)methanol 

Downstream Products

• 1168721-90-1 (E)-3-((1H-indazol-6-yl)methylene)-5-methoxyindolin-2-one 
• 1402728-95-3 (1E,6E)-1-(1H-benzotriazol-5-yl)-7-[2-methoxy-4-(2-pyridylmethoxy)phenyl]hepta-1,6-diene-3,5-dione 

Relevant academic research and scientific papers

NOVEL HETEROCYCLIC DERIVATIVES WITH CARDIOMYOCYTE PROLIFERATION ACTIVITY FOR TREATMENT OF HEART DISEASES

Provided are novel heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases. Specifically, provided are the compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs, prepa

Substituted Pyran Derivatives

Certain 3,6-disubstituted and 2, 4, 5-trisubstituted pyran derivatives that exhibit potent activity on monoamine transport systems are provided. The 3, 6 and 2, 4, 5 pyrans are useful in probing the effects of their binding to monoamine transporter system

NOVEL CURCUMIN DERIVATIVE

The present invention provides a novel compound that is structurally similar to curcumin and has a suppressive effect on Aβ aggregation, a degradative effect on Aβ aggregates, an inhibitory effect on β-secretase, and a protective effect on neurons. The novel compound is a compound represented by the following general formula (Ia) or a salt thereof: wherein R1 represents a 4-hydroxy-3-methoxyphenyl group or the like, and R2 represents a 1H-indol-6-yl group or the like.

INDAZOLYL, BENZIMIDAZOLYL, BENZOTRIAZOLYL SUBSTITUTED INDOLMONE DERIVATIVES AS KINASE INHIBITORS USEFUL IN THE TREATMENT OF CANCER

The present invention is directed to a compound is represented by Structural Formula (A):or a pharmaceutically acceptable salt therof. The present invention is also directed to a pharmaceutical composition comprising a compound represented by Structural Formula (A) described above or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier or diluent. Also disclosed is a method of treating a subject having cancer, wherein the method comprises administering a therapeutically effective amount of a compound represented by Structural Formula (A) described above or a pharmaceutically acceptable salt thereof.

Synthesis and practical use of 1H-1,2,3-benzotriazole-5-carboxaldehyde for reductive amination

A reliable synthetic procedure to obtain multigram quantities of 1H-1,2,3-benzotriazole-5-carboxaldehyde has been developed. This material can be used in reductive amination reactions with primary and secondary amines to provide good to excellent yields o

Novel potent antagonists of transient receptor potential channel, vanilloid subfamily member 1: Structure-activity relationship of 1,3-diarylalkyl thioureas possessing new vanilloid equivalents

Recently, 1,3-diarylalkyl thioureas have merged as one of the promising nonvanilloid TRPV1 antagonists possessing excellent therapeutic potential in pain regulation. In this paper, the full structure-activity relationship for TRPV1 antagonism of a novel series of 1,3-diarylalky thioureas is reported. Exploration of the structure-activity relationship, by systemically modulating three essential pharmacophoric regions, led to six examples of 1,3-dibenzyl thioureas, which exhibit Ca2+ uptake inhibition in rat DRG neuron with IC50 between 10 and 100 nM.

ANABASEINE DERIVATIVES USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISEASES

The compounds of the present invention are of formula (I): wherein A, R3, R4 is as defined herein, are useful as ligands for nicotinic receptors.