4917-74-2

Basic information

• Product Name: 2-amino-1-methyl-2-thioxoethyl benzoate
• CAS NO: 4917-74-2
• Molecular Formula: C₁₀H₁₁NO₂S
• Molecular Weight: 209.2648
• Mol File: 4917-74-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 360.1°C at 760 mmHg
• Flash Point: 171.6°C
• Density: 1.235g/cm³
• Vapor Pressure: 2.27E-05mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: 2-amino-1-methyl-2-thioxoethyl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-1-methyl-2-thioxoethyl benzoate(4917-74-2)
• EPA Substance Registry System: 2-amino-1-methyl-2-thioxoethyl benzoate(4917-74-2)

Safety Data

• Hazardous Substances Data: 4917-74-2(Hazardous Substances Data)

Usage

Type

Synthetic organic compound

Use

Carbonic anhydrase inhibitor in the treatment of glaucoma, epilepsy, and certain types of edema

Mechanism of action

Inhibits the enzyme carbonic anhydrase, reducing production of aqueous humor in the eye and regulating pH in the brain and other tissues

Forms available

Oral and injectable

Side effects

Drowsiness, fatigue, loss of appetite

Upstream product

• 19172-47-5 Lawessons reagent 
• 23427-66-9 2-benzoyloxy-propionic acid amide 
• 98-88-4 benzoyl chloride 
• 102-71-6 triethanolamine 
• 98777-16-3 2-benzoyloxy-1-butyronitrile 

Downstream Products

• 408318-86-5 1-benzoyloxy-1-(4-methyl-thiazol-2-yl)-ethane 
• 2409-45-2 1-benzoyloxy-1-[4-(4-nitro-phenyl)-thiazol-2-yl]-ethane 
• 80337-75-3 2'-<1-(benzyloxy)ethyl>-2,4'-bithiazole-4-carboxylate 
• 65823-87-2 1-(4-p-tolyl-thiazol-2-yl)-ethanol 
• 76275-85-9 ethyl 2-<1-(benzoyloxy)ethyl>thiazole-4-carboxylate 
• 21478-61-5 benzoic acid-(1-thiazol-2-yl-ethyl ester) 
• 849048-44-8 1-benzoyloxy-1-(4-phenyl-thiazol-2-yl)-ethane 
• 100956-45-4 2-[2-(1-benzoyloxy-ethyl)-4-methyl-thiazol-5-yl]-ethanol 

Relevant articles and documents

Synthesis of some spin-labeled bithiazoles, useful probes for studying bleomycin-DNA binding

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MEDICINAL COMPOSITIONS

The present invention relates to an agent for the prophylaxis or treatment of pain, an agent for suppressing activation of osteoclast, and an inhibitor of osteoclast formation, which contains a p38 MAP kinase inhibitor and/or a TNF-α production inhibitor.

A Convenient Synthesis of Methyl 2-thazoline-4-carboxylate, an Important Skeleton of Cyclothiazomycin

The convenient syntheses of a few methyl 2-(1-amino)alkenyl thiazoline-4-carboxylates and methyl 2-thiazoline-4-carboxylate have been accomplished.The latter is an important portial skeleton of macrobicyclic peptide antibiotic cyclothiazomycin.