76275-85-9Relevant academic research and scientific papers
Total synthesis of myxothiazols, novel bis-thiazole β-methoxyacrylate- based anti-fungal compounds from myxobacteria
Clough, John M.,Dube, Henry,Martin, Bruce J.,Pattenden, Gerald,Reddy, K. Srinivasa,Waldron, Ian R.
, p. 2906 - 2911 (2008/02/09)
Convergent total syntheses of myxothiazols A and Z are described. The syntheses are based on elaboration of the (S)-E,E-diene thioamide 22, conversion of 22 into the bis-thiazole 27 and Wittig reactions between 27c and the aldehyde 30. The substituted β-m
A Convenient Synthesis of Methyl 2-thazoline-4-carboxylate, an Important Skeleton of Cyclothiazomycin
Shin, Chung-gi,Ito, Akio,Okumura, Kazuo,Nakamura, Yutaka
, p. 45 - 46 (2007/10/02)
The convenient syntheses of a few methyl 2-(1-amino)alkenyl thiazoline-4-carboxylates and methyl 2-thiazoline-4-carboxylate have been accomplished.The latter is an important portial skeleton of macrobicyclic peptide antibiotic cyclothiazomycin.
