4917-96-8

Upstream product

• 2510-77-2 α-benzoyldiphenylmethyl chloride 
• 64-19-7 acetic acid 
• 7714-70-7 2-methoxy-2,3,3-triphenyl-oxirane 
• 71-43-2 benzene 
• 6905-43-7 2-bromo-1,2,2-triphenyl-ethanone 
• 1733-63-7 1,2,2-triphenylethan-1-one 
• 4237-46-1 α-phenylbenzoin 
• 75-36-5 acetyl chloride 
• 5457-37-4 methoxy-2 triphenyl-1,2,2 ethanone-1 
• 108-24-7 acetic anhydride 

Relevant academic research and scientific papers

2-Hydroxy-1,2,2-triphenylethanone as an efficient photolabile protecting group for carboxylic acids

The synthesis is reported of 2-hydroxy-1,2,2-triphenylethanone esters of carboxylic acids by the reaction between 2-chloro-1,2,2-triphenylethanone and a carboxylic acid in the presence of silver carbonate and silver tetrafluoroborate. Photolysis of the esters occurs rapidly on irradiation with a medium-pressure mercury lamp through quartz or Pyrex to return the carboxylic acid. The side product of the photolysis is benzo[b]phenanthro[9,10-d]furan, formed through a tandem process involving initial generation of 2,3-diphenylbenzofuran, photochemical cyclisation and re-aromatisation by aerial oxidation.

Synthesis and photolysis studies of carboxylic esters of 2-hydroxy-1,2,2-triphenylethanone: A novel tandem photocyclisation

Carboxylic esters of 2-hydroxy-1,2,2-triphenylethanone can be prepared in good yield by reaction between 2-chloro-1,2,2-triphenylethanone and a carboxylic acid in the presence of silver carbonate and silver tetrafluoroborate. Irradiation of the ester with a medium pressure mercury lamp results in a rapid and quantitative photolysis to afford the carboxylic acid and benzo[b]phenanthro[9,10-d]furan.